Huang Zhenzhou, Yu Keyi, Fang Yujie, Dai Hang, Cai Hongyan, Li Zhenpeng, Kan Biao, Wei Qiang, Wang Duochun
National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), State Key Laboratory of Infectious Disease Prevention and Control, Beijing 102206, China.
Center for Human Pathogenic Culture Collection, China CDC, Beijing 102206, China.
Microorganisms. 2020 Apr 13;8(4):555. doi: 10.3390/microorganisms8040555.
The genus is ubiquitous in marine environments and uses numerous evolutionary characteristics and survival strategies in order to occupy its niche. Here, a newly identified species, , was deeply explored to reveal a unique environmental adaptability. type strain FJ201301 shared 817 core genes with the species in the population genomic analysis, but possessed unique genes of its own. In addition, FJ201301 was predicated to carry 106 virulence-related factors, several of which were mostly found in other pathogenic species. Moreover, a comparative transcriptome analysis between the low-salt (1% NaCl) and high-salt (8% NaCl) condition was conducted to identify the genes involved in salt tolerance. A total of 913 unigenes were found to be differentially expressed. In a high-salt condition, 577 genes were significantly upregulated, whereas 336 unigenes were significantly downregulated. Notably, differentially expressed genes have a significant association with ribosome structural component and ribosome metabolism, which may play a role in salt tolerance. Transcriptional changes in ribosome genes indicate that may have gained a predominant advantage in order to adapt to the changing environment. In conclusion, to survive in adversity, has enhanced its environmental adaptability and developed various strategies to fill its niche.
该属在海洋环境中广泛存在，并利用众多进化特征和生存策略来占据其生态位。在此，对一个新鉴定的物种进行了深入研究，以揭示其独特的环境适应性。在群体基因组分析中，该物种的模式菌株FJ201301与同属物种共享817个核心基因，但拥有自身独特的基因。此外，预测FJ201301携带106个与毒力相关的因子，其中一些因子大多在其他致病性同属物种中发现。此外，还进行了低盐（1% NaCl）和高盐（8% NaCl）条件下的比较转录组分析，以鉴定参与耐盐性的基因。共发现913个单基因差异表达。在高盐条件下，577个基因显著上调，而336个单基因显著下调。值得注意的是，差异表达基因与核糖体结构成分和核糖体代谢显著相关，这可能在耐盐性中发挥作用。核糖体基因的转录变化表明该物种可能获得了显著优势以适应不断变化的环境。总之，为了在逆境中生存，该物种增强了其环境适应性，并制定了各种策略来占据其生态位。
