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CRISPR-Cas13a system: a novel approach to precision oncology.

作者信息

Zhang Junxia, You Yongping

机构信息

Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.

Institute for Brain Tumors, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing 210029, China.

出版信息

Cancer Biol Med. 2020 Feb 15;17(1):6-8. doi: 10.20892/j.issn.2095-3941.2019.0325.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f41c/7142841/c04070ae5fd5/cbm-17-006-g001.jpg

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The CRISPR-Cas13a Gene-Editing System Induces Collateral Cleavage of RNA in Glioma Cells.
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Genome-Wide CRISPR-Cas9 Screening Identifies NF-κB/E2F6 Responsible for EGFRvIII-Associated Temozolomide Resistance in Glioblastoma.
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