Yulia Angela, Pawar Sona, Chelemen Oana, Ushakov Fred, Pandya Pranav P
Fetal Medicine Unit, Elizabeth Garrett Anderson Wing, University College London Hospital, London, England.
J Ultrasound Med. 2020 Sep;39(9):1857-1863. doi: 10.1002/jum.15280. Epub 2020 Apr 15.
Hemivertebra appears as an angulation of the spine on a coronal section. We evaluated the prevalence of chromosomal defects and outcome of fetuses with hemivertebra detected in the first trimester over a 9-year period in a single tertiary referral unit. There were 10 cases; 9 had other anomalies. Seven couples opted for termination of pregnancy. One pregnancy ended in fetal demise at 16 weeks, and the 2 isolated cases continued the pregnancy with delivery at term. A karyotype analysis was performed in 8 fetuses: 5 found to be euploid and 3 having trisomy 18. Comprehensive ultrasound screening allows early prenatal detection and appropriate counseling.
半椎体在冠状面上表现为脊柱的成角。我们在一家单一的三级转诊单位评估了9年期间孕早期检测出半椎体胎儿的染色体缺陷患病率及结局。共有10例；9例有其他异常。7对夫妇选择终止妊娠。1例妊娠在16周时胎儿死亡，2例孤立病例继续妊娠并足月分娩。对8例胎儿进行了核型分析：5例为整倍体，3例为18三体。全面的超声筛查可实现产前早期检测并提供适当的咨询。
