Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi 835215, Jharkhand, India.
Department of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, Gandhinagar, Gujarat 382355, India.
Comb Chem High Throughput Screen. 2020;23(7):624-648. doi: 10.2174/1386207323666200416150754.
The Arisaema (Araceae) is a genus of approximately 180 perennial herbs widely distributed in the evergreen and deciduous forests. This genus (Arisaema) has been used as a medicinal agent since ancient times. Experimental investigations have shown a promising positive correlation with its folklore claim and this encourages us to report updated medicinal review (genus Arisaema) for future research.
This review aimed to summarize the ethnobotany, folklore uses, chemistry and biological activities.
The comprehensive literature on genus Arisaema indicates the presence of terpenoids, flavonoids, and glycosphingolipids as the principal chemical constituents. Additionally, phytosterols, alkaloids, carboline derivatives and miscellaneous compounds were documented in plants of genus Arisaema. Biological investigations led to the credentials of antioxidant, anticancer, insecticidal, antimicrobial, anthelmintic and hepatoprotective activities. Following, several plant species are promising candidates for the treatment of cancer, parasitic diseases and microbial infection complications. Though, a lot of facets of this genus like phytoconstituents identification, mechanistic profile, adverse effects and clinical studies are still quite limited. Thus, this systematic review may act as a powerful tool in future studies for promoting health benefits against various health hazards.
天南星科（Araceae）是一个约有 180 种多年生草本植物的属，广泛分布于常绿和落叶森林中。自古以来，该属（天南星属）就被用作药物。实验研究表明，它与民间传说的说法之间存在着令人鼓舞的积极关联，这促使我们报告更新的药用综述（天南星属），以供未来的研究。
本综述旨在总结天南星属的民族植物学、民间用途、化学和生物活性。
天南星属的综合文献表明，萜类、类黄酮和糖脂是主要的化学成分。此外，植物甾醇、生物碱、咔啉衍生物和杂类化合物也在天南星属植物中被记录下来。生物学研究证实了抗氧化、抗癌、杀虫、抗菌、驱虫和保肝活性。随后，一些植物物种有望成为治疗癌症、寄生虫病和微生物感染并发症的候选药物。然而，该属的许多方面，如植物成分的鉴定、机制概况、不良反应和临床研究仍然相当有限。因此，本系统综述可能成为未来研究的有力工具，以促进对各种健康危害的健康益处。
