胃内球囊对超重和肥胖成年人减肥的疗效：一项随机对照试验的系统评价和荟萃分析
Efficacy of Intragastric Balloons for Weight Loss in Overweight and Obese Adults: a Systematic Review and Meta-analysis of Randomized Controlled Trials.
作者信息
Kotinda Ana Paula Samy Tanaka, de Moura Diogo Turiani Hourneaux, Ribeiro Igor Braga, Singh Shailendra, da Ponte Neto Alberto Machado, Proença Igor Mendonça, Flor Marcelo Mochate, de Souza Karina Lopes, Bernardo Wanderley Marques, de Moura Eduardo Guimarães Hourneaux
机构信息
Gastrointestinal Endoscopy Unit, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
, Av. Dr Enéas de Carvalho Aguiar, 225, 6o andar, bloco 3, Cerqueira Cesar, São Paulo, SP, 05403-010, Brazil.
出版信息
Obes Surg. 2020 Jul;30(7):2743-2753. doi: 10.1007/s11695-020-04558-5.
Intragastric balloons (IGB) are the most widely used endoscopic bariatric and metabolic therapies. We aimed to evaluate the efficacy of IGB in comparison with sham or lifestyle interventions for weight loss in overweight and obese patients. This systematic review and meta-analysis was performed following the PRISMA guidelines. Electronic searches were performed to identify randomized controlled trials, which compared IGB with sham or lifestyle intervention. Thirteen RCTs with 1523 patients were included. The difference in mean %EWL and %TWL at follow-up was 17.98%, and 4.40%, respectively, which was significantly higher in the IGB group. Similarly, the difference in mean AWL and BMIL was 6.12 kg, and 2.13 kg/m, respectively. IGB therapy is more effective than lifestyle intervention alone for weight loss in overweight and obese adults.
胃内球囊（IGB）是应用最为广泛的内镜下减肥和代谢治疗方法。我们旨在评估胃内球囊与假手术或生活方式干预相比，对超重和肥胖患者体重减轻的疗效。本系统评价和荟萃分析按照PRISMA指南进行。通过电子检索识别比较胃内球囊与假手术或生活方式干预的随机对照试验。纳入了13项随机对照试验，共1523例患者。随访时平均超重体重减轻百分比（%EWL）和总体重减轻百分比（%TWL）的差异分别为17.98%和4.40%，IGB组显著更高。同样，平均实际体重减轻（AWL）和体重指数降低（BMIL）的差异分别为6.12千克和2.13千克/米²。对于超重和肥胖成年人，胃内球囊治疗在减肥方面比单纯生活方式干预更有效。
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