LADISER Inmunología y Biología Molecular, Facultad de Ciencias Químicas, Universidad Veracruzana, Prolongación Oriente 6, No. 1009, Col. Rafael Alvarado, Orizaba, Mexico.
Instituto de Salud Pública, Universidad Veracruzana, Av. Luis Castelazo Ayala, s/n., Col. Industrial Ánimas, 91190, Xalapa, Veracruz, Mexico.
Acta Parasitol. 2020 Sep;65(3):661-668. doi: 10.2478/s11686-020-00197-z. Epub 2020 Apr 16.
The state of Veracruz, Mexico, is a well-recognized endemic region for Chagas disease, but congenital transmission has not been extensively studied. We estimated here the prevalence and the risk of congenital transmission of Trypanosoma cruzi in pregnant women from 27 municipalities of central Veracruz.
528 sera from pregnant women were analyzed by ELISA and IFA assays for the detection of IgG antibodies against T. cruzi.
The presence of anti-T. cruzi antibodies was identified in women from 17 municipalities, obtaining an overall seroprevalence of 17.0%. A higher seropositivity was observed in the municipalities of Orizaba (25.2%), Nogales (13.6%), and Río Blanco (10.5%). The results suggest that there is a high risk of congenital transmission of T. cruzi in the region.
There are currently limited actions for the surveillance and control of congenital transmission of Chagas disease in Veracruz.
墨西哥韦拉克鲁斯州是一个公认的恰加斯病地方性流行区，但先天性传播尚未得到广泛研究。我们在此估计了来自韦拉克鲁斯州中部 27 个城市的孕妇中克氏锥虫的流行率和先天性传播的风险。
通过 ELISA 和 IFA 检测 528 份孕妇血清，检测 IgG 抗体对 T. cruzi 的反应。
在来自 17 个城市的妇女中发现了抗 T. cruzi 抗体，总血清阳性率为 17.0%。在奥里萨巴（25.2%）、诺加莱斯（13.6%）和里奥布兰科（10.5%）等城市观察到更高的血清阳性率。结果表明，该地区存在克氏锥虫先天性传播的高风险。
目前，韦拉克鲁斯州对先天性传播的恰加斯病的监测和控制行动有限。
