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[消化系统癌症的卵巢转移。诊断与治疗管理]

[Ovarian metastases of digestive cancers. Diagnostic and therapeutic management].

作者信息

Lorimier G, Reigner B, Rive C, Cronier P, Talha A, Guntz M

机构信息

Clinique Chirurgicale A, C.H.U. Angers.

出版信息

J Chir (Paris). 1988 Dec;125(12):699-703.

PMID:3230108
Abstract

Although ovarian metastasis of digestive cancers were well known since more 80 years, the management of ovaries is still discussed. The authors reviewed 112 cases of digestive tumors in female patients operated between 1973 and 1987, excluding the peritoneal carcinomatosis, and report 7 cases of ovarian metastasis. The primary carcinoma was gastric (2 cases) colonic (2 cases) appendicular (1 case) small bowel (1 case) and biliary tract (1 case). Because the severe prognosis and the frequent revealing and isolated feature of the ovarian metastases the authors review the literature in order to propose recommendations regarding the diagnosis and treatment according to the localisation, the grading of the primary tumor particularly in non menopausal patients. When the primary tumor is a mucinous signet-ring carcinoma with spread to the serosa and a gross abnormality of an ovary is discovered the oophorectomy should be performed. In every cases an immediate histological examination is absolutely necessary. Clinical and sonographic findings are included in the operative staging and the follow up of patients operated for a digestive adenocarcinoma. Especially if the ovarian tumor is bilateral a complete digestive check-up including appendix and biliary tract is necessary.

摘要

尽管消化系统癌症的卵巢转移早在80多年前就为人所知,但卵巢转移癌的治疗仍存在争议。作者回顾了1973年至1987年间接受手术的112例女性消化系统肿瘤患者(不包括腹膜癌),报告了7例卵巢转移癌。原发癌分别为胃癌(2例)、结肠癌(2例)、阑尾癌(1例)、小肠癌(1例)和胆管癌(1例)。鉴于卵巢转移癌预后严重,且常以孤立性表现出现,作者回顾了相关文献,以便根据原发肿瘤的部位、分级,特别是针对非绝经患者,提出有关诊断和治疗的建议。当原发肿瘤为黏液性印戒细胞癌且已侵犯浆膜,同时发现卵巢有明显异常时,应行卵巢切除术。在所有病例中,立即进行组织学检查绝对必要。临床和超声检查结果应纳入接受消化系统腺癌手术患者的手术分期及随访中。特别是当卵巢肿瘤为双侧时,需要进行包括阑尾和胆管在内的全面消化系统检查。

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