Rheumatology/Clinical Immunology, University Hospital Würzburg, Germany.
Centre for Interdisciplinary Rheumatology, Clinical Immunology and Autoimmune Diseases INDIRA and Internal Medicine II, University Hospital Tübingen, Germany.
Clin Exp Rheumatol. 2020 May-Jun;38 Suppl 125(3):59-64. Epub 2020 Apr 14.
To assess and compare sexual dysfunction (SDF) in female patients with systemic sclerosis (SSc) or systemic lupus erythematosus (SLE), to correlate sexual function with disease characteristics and depression, and to evaluate a short questionnaire (Qualisex) as a screening test.
Female patients with systemic sclerosis or systemic lupus erythematosus in two German tertiary university hospitals were evaluated in a prospective study. A self-designed questionnaire, the Female Sexual Function Index (FSFI), the Qualisex, and the Beck's depression inventory were used.
171 female patients were included into the study (83 with SSc, and 88 with SLE). 62.6% (52 of 83) of SSc patients and 67.0% (59 of 88) of SLE patients were sexually active. Only 9.6% of SSc patients and 14.8% of SLE patients had ever discussed sexual problems with their physician. Significantly more SSc patients would wish to discuss sexuality with their physician more intensively (37.3% vs. 28.4% in SLE patients, p=0.011). Among the 51 sexually active and evaluable SSc patients a mean FSFI of 25.53 (±5.06) was found, with a FSFI value defining sexual dysfunction (SDF) (<26.55) in 49% of patients, which did not differ significantly compared to SLE patients (n=59, mean FSFI 26.92 (±5.17), SDF in 45.8%). The Qualisex correlated significantly with the FSFI, and both Qualisex and FSFI correlated with depressiveness.
Sexual dysfunction (SDF) is a frequent problem in female patients with SSc and SLE. Addressing sexual issues during medical consultation is an unmet need. The Qualisex constitutes a short questionnaire, which is suitable for addressing concerns on sexuality.
评估和比较系统性硬化症（SSc）或系统性红斑狼疮（SLE）女性患者的性功能障碍（SDF），将性功能与疾病特征和抑郁相关联，并评估一个简短的问卷（Qualisex）作为筛查试验。
在德国两所三级大学医院的前瞻性研究中，评估了系统性硬化症或系统性红斑狼疮的女性患者。使用了自我设计的问卷、女性性功能指数（FSFI）、Qualisex 和贝克抑郁量表。
共纳入 171 名女性患者（83 名 SSc 患者和 88 名 SLE 患者）。62.6%（83 名 SSc 患者中的 52 名）和 67.0%（88 名 SLE 患者中的 59 名）的患者有性生活。只有 9.6%的 SSc 患者和 14.8%的 SLE 患者曾与医生讨论过性问题。有明显更多的 SSc 患者希望更深入地与医生讨论性问题（37.3% vs. SLE 患者中的 28.4%，p=0.011）。在 51 名有性生活且可评估的 SSc 患者中，平均 FSFI 为 25.53（±5.06），49%的患者存在性功能障碍（SDF）（<26.55），与 SLE 患者无显著差异（n=59，平均 FSFI 26.92（±5.17），SDF 占 45.8%）。Qualisex 与 FSFI 显著相关，且两者均与抑郁相关。
性功能障碍（SDF）是 SSc 和 SLE 女性患者的常见问题。在医疗咨询中解决性问题是未满足的需求。Qualisex 是一个简短的问卷，适用于解决性问题。
