Jenkins K J, Griffith G, Kramer J K
Animal Research Centre, Agriculture Canada, Ottawa, Ontario.
J Dairy Sci. 1988 Nov;71(11):3003-12. doi: 10.3168/jds.S0022-0302(88)79898-7.
This study compared plasma lipoprotein fraction profiles and lipid composition in the calf at 3 d, 3 wk, and 12 wk (weaned). For all ages the major plasma lipoprotein fraction was high density lipoproteins (52 to 73%), followed by very high density lipoproteins (10 to 22%), low density lipoproteins (13 to 18%), and chylomicrons plus very low density lipoproteins (5 to 9%). Most plasma lipid was cholesterol esters (41 to 49%) and phosphatidylcholine (21 to 29%). Most cholesterol esters (66 to 81%) and phosphatidylcholine (68 to 80%) were in high density lipoproteins; free fatty acids (83 to 96%) and lysophosphatidylcholine (75 to 85%) in very high density lipoproteins; and triglycerides (93 to 98%) in the remaining lipoprotein fractions. Of the three ages studied, 3-d-old calves had comparatively low plasma total lipids, high density lipoproteins, cholesterol esters, phosphatidylcholine, and linoleic acid in all lipid classes; they had relatively high plasma very high density lipoproteins, triglycerides, free fatty acids, phosphatidylethanolamine, and 20:3 n-9 fatty acid (indicative of essential fatty acids deficiency). Lipoprotein classes and lipid composition were similar at wk 3 and 12. Comparison of fatty acid profiles for phosphatidylcholine with those for lysophosphatidylcholine and cholesterol esters indicated plasma lecithin-cholesterol acyltransferase was active in calves at all three ages studied.
本研究比较了犊牛在3日龄、3周龄和12周龄（断奶时）的血浆脂蛋白组分谱和脂质组成。在所有年龄段，主要的血浆脂蛋白组分是高密度脂蛋白（52%至73%），其次是极高密度脂蛋白（10%至22%）、低密度脂蛋白（13%至18%）以及乳糜微粒加极低密度脂蛋白（5%至9%）。大部分血浆脂质是胆固醇酯（41%至49%）和磷脂酰胆碱（21%至29%）。大部分胆固醇酯（66%至81%）和磷脂酰胆碱（68%至80%）存在于高密度脂蛋白中；游离脂肪酸（83%至96%）和溶血磷脂酰胆碱（75%至85%）存在于极高密度脂蛋白中；甘油三酯（93%至98%）存在于其余的脂蛋白组分中。在所研究的三个年龄段中，3日龄的犊牛血浆总脂质、高密度脂蛋白、胆固醇酯、磷脂酰胆碱以及所有脂质类别中的亚油酸含量相对较低；它们的血浆极高密度脂蛋白、甘油三酯、游离脂肪酸、磷脂酰乙醇胺和20:3 n-9脂肪酸（表明必需脂肪酸缺乏）含量相对较高。3周龄和12周龄时脂蛋白类别和脂质组成相似。将磷脂酰胆碱的脂肪酸谱与溶血磷脂酰胆碱和胆固醇酯的脂肪酸谱进行比较表明，在所研究的所有三个年龄段的犊牛中，血浆卵磷脂胆固醇酰基转移酶均具有活性。
