Ishak A W, Persak G C, Mitchell P C, Warwick S
Omni Eye Services of Wilmington, DE 19808.
J Am Optom Assoc. 1988 Nov;59(11):864-8.
Giant cell arteritis is a visually devastating disease that primarily affects the over 55 age group. This granulomatous inflammation affects large and medium-sized arteries anywhere in the body. Systemic manifestations of this disease include: jaw claudication, scalp tenderness, malaise and vertigo. Decreased appetite and/or anorexia may also be seen. Ocular manifestations may include ischemic optic neuropathy with sudden markedly reduced visual acuity. Steroid treatment is used to protect the uninvolved eye. In its classic form the disease is monitored by adjusting the steroid dosage with the erythrocyte sed rate (ESR). Prognosis for visual restoration in the involved eye is poor.
巨细胞动脉炎是一种严重影响视力的疾病，主要累及55岁以上人群。这种肉芽肿性炎症会影响身体任何部位的大中型动脉。该疾病的全身表现包括：颌部间歇性运动障碍、头皮压痛、不适和眩晕。也可能出现食欲减退和/或厌食。眼部表现可能包括缺血性视神经病变，视力会突然明显下降。使用类固醇治疗来保护未受累的眼睛。在其典型形式中，通过根据红细胞沉降率（ESR）调整类固醇剂量来监测疾病。受累眼睛视力恢复的预后较差。
