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利用腹膜间置瓣预防机器人辅助根治性前列腺切除术和双侧盆腔淋巴结清扫术后症状性淋巴囊肿。

Utilization of a Peritoneal Interposition Flap to Prevent Symptomatic Lymphoceles After Robotic Radical Prostatectomy and Bilateral Pelvic Lymph Node Dissection.

机构信息

Department of Urology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.

出版信息

J Endourol. 2020 Aug;34(8):821-827. doi: 10.1089/end.2020.0073. Epub 2020 May 13.

Abstract

The peritoneal interposition flap (PIF) has been shown to prevent postoperative symptomatic lymphocele (SL) formation after robot-assisted radical prostatectomy (RARP) and pelvic lymph node dissection (PLND). The PIF inhibits the mobilized bladder from resealing over its lateral dissection planes, which overly the lymphadenectomy beds. This creates a window for lymphatic fluid to drain into the peritoneal cavity where it can be absorbed. Herein, we externally validate its utility in preventing postoperative SL formation and assess its effect on postoperative urinary function. We retrospectively reviewed all consecutive patients who underwent RARP with bilateral PLND by a single surgeon between July 2016 and September 2019. All patients who underwent surgery before August 8, 2018 did not receive the PIF, while those who underwent surgery after August 8, 2018 received the PIF. Our PIF technique involves fixing the peritoneum overlying the lateral dome of the bladder to the ipsilateral, anterior-lateral surface of the bladder using a barbed absorbable suture. Continuous and categorical variables were compared between the two groups using independent -tests and chi-square tests, respectively;  < 0.05 was considered significant. Of 318 total patients, 201 did not undergo the PIF and 117 underwent the PIF. With regard to postoperative complications, patients undergoing the PIF had a lower incidence of SL compared with those not undergoing the PIF (0.0% 6.0%,  = 0.007). There was no difference in 30-day postoperative nonlymphocele complications (Clavien >2) between both groups ( = 0.800). With regard to urinary function, there was no difference in the rate of 3-month postoperative continence ( = 0.624), preoperative American Urological Association Symptom Score (AUASS) ( = 0.898), and postoperative AUASS ( = 0.470) between both groups. Utilization of a PIF may minimize the risk of SL formation after RARP and PLND without increasing the risk of non-SL-related complications. This technique does not adversely affect postoperative urinary function.

摘要

腹膜间置瓣(PIF)已被证明可预防机器人辅助根治性前列腺切除术(RARP)和盆腔淋巴结清扫术(PLND)后术后症状性淋巴囊肿(SL)的形成。PIF 可防止被移动的膀胱重新封闭其侧面切开平面,这些平面覆盖淋巴结切除术床。这为淋巴液排入腹膜腔并被吸收创造了一个窗口。在此,我们对其预防术后 SL 形成的实用性进行外部验证,并评估其对术后尿功能的影响。

我们回顾性分析了 2016 年 7 月至 2019 年 9 月期间由同一位外科医生行 RARP 加双侧 PLND 的所有连续患者。2018 年 8 月 8 日前手术的所有患者均未接受 PIF,而 2018 年 8 月 8 日后手术的患者接受了 PIF。我们的 PIF 技术包括使用带倒钩的可吸收缝线将覆盖膀胱侧穹窿的腹膜固定到膀胱同侧前外侧表面。两组间连续和分类变量分别采用独立样本 t 检验和卡方检验进行比较; < 0.05 为差异有统计学意义。

在 318 例患者中,201 例未行 PIF,117 例行 PIF。在术后并发症方面,行 PIF 的患者与未行 PIF 的患者相比,SL 发生率较低(0.0% 6.0%, = 0.007)。两组间 30 天非淋巴囊肿相关并发症(Clavien >2)发生率无差异( = 0.800)。在尿功能方面,两组间 3 个月后控尿率( = 0.624)、术前美国泌尿外科学会症状评分(AUASS)( = 0.898)和术后 AUASS( = 0.470)无差异。

在 RARP 和 PLND 后使用 PIF 可能会降低 SL 形成的风险,而不会增加非 SL 相关并发症的风险。该技术不会对术后尿功能产生不利影响。

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