State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, the Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, China; School of Life Sciences, Guangzhou University, Guangzhou 510006, China; Guangdong Laboratory of Lingnan Modern Agricultural Science and Technology, Guangzhou 510642, China.
State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, the Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, China.
Curr Opin Plant Biol. 2020 Jun;55:60-65. doi: 10.1016/j.pbi.2020.03.006. Epub 2020 Apr 15.
Nitrogen (N) is the most abundant mineral elements in plants, and the application of inorganic N fertilizer makes huge contribution to the crop production and global food security. However, low N use efficiency (NUE) and overapplication of N fertilizers causes ever-growing environmental problems. Understanding the molecular mechanisms of N sensing and signalling in plants will provide molecular basis for NUE improvement of crops. Forward genetics screening and functional analysis have characterized the NRT1.1-NLP centered N signalling pathway at the cellular level. With the incorporation of systems biology approaches, a preliminary N regulatory network has been delineated. Meanwhile, long-distance N signalling has also been unveiled at the whole plant level. This review highlights most recent understanding of the N signalling network in plants, and also discusses how to further integrate hierarchical regulation of N signalling in plants.
氮（N）是植物中含量最丰富的矿物质元素，无机 N 肥料的应用为作物生产和全球粮食安全做出了巨大贡献。然而，低氮利用效率（NUE）和过量施用氮肥导致环境问题日益严重。了解植物中氮感应和信号转导的分子机制将为提高作物的 NUE 提供分子基础。正向遗传学筛选和功能分析已经在细胞水平上描述了以 NRT1.1-NLP 为中心的氮信号通路。随着系统生物学方法的加入，初步的氮调控网络已经被描绘出来。同时，在整个植物水平上也揭示了长距离氮信号转导。本文综述了植物中氮信号网络的最新研究进展，并讨论了如何进一步整合植物中氮信号的层次调节。
