Oyama T, Joshita T, Tanami Y, Ishida T, Izuo M
Dept. of Clinical Lab., Gunma Univ. School of Med.
Gan No Rinsho. 1988 Dec;34(15):2067-74.
Intranuclear cytoplasmic inclusions (ICI) in 38 cases of thyroid papillary carcinomas have been studied as to the relationship between the frequency of ICI and the clinical, histological, and cytological findings of the carcinoma. ICI were present in all cases. The frequency of ICI in the cases studied ranged from +/- (one per several fields) to ¿ (more than ten per one field), using a microscope of 400 magnifications, and from 1.3% to 11.6% (mean value: 3.9%) of the nuclei of the carcinomas. The frequency of ICI was found to be influenced by the state of the nuclear chromatin and pleomorphism, but was not influenced by the papillary or follicular tumor growth. The relationship between the frequency of ICI and the tumor size and the existence of lymph-nodes metastasis, however, was not clarified.
对38例甲状腺乳头状癌的核内细胞质包涵体（ICI）进行了研究，以探讨ICI的出现频率与癌的临床、组织学及细胞学表现之间的关系。所有病例均有ICI。在400倍显微镜下，所研究病例中ICI的出现频率为每几个视野有1个（±）至每1个视野有10个以上（¿），占癌细胞核的1.3%至11.6%（平均值：3.9%）。发现ICI的出现频率受核染色质状态和多形性的影响，但不受乳头状或滤泡状肿瘤生长方式的影响。然而，ICI的出现频率与肿瘤大小及淋巴结转移的存在之间的关系尚不清楚。
