Department of Interventional Radiology, Brigham and Women's Hospital, Boston, MA.
Department of Interventional Radiology, Beth Israel Deaconess Medical Center, Boston, MA.
Curr Probl Diagn Radiol. 2021 Nov-Dec;50(6):961-966. doi: 10.1067/j.cpradiol.2020.03.001. Epub 2020 Apr 8.
Extra-adrenal functional neuroendocrine neoplasms are termed paragangliomas. We describe a case of a large abdominal neuroendocrine tumor that was proved to be a paraganglioma on biopsy. Unfortunately, the patient presented with high output heart failure, an extremely rare complication of paraganglioma. Prior to surgical biopsy, the patient underwent a complete invasive and non-invasive cardiac workup, in addition to biochemical testing. On a PET CT, the retroperitoneal neuroendocrine tumor was shown to have been metastasized to the spine. Chemotherapy targeted at somatostatin analogs was initiated. The unique presentation and rare complications are presented with relevant review of literature to highlight the spectrum of disease geared towards diagnostic and interventional radiologists. It is crucial to understand the broad spectrum of disease and include this entity in the differential diagnosis of a retroperitoneal mass. Equally significant is to consider potential complications such as metastases and cardiac failure to guide appropriate workup and management.
肾上腺外功能性神经内分泌肿瘤被称为副神经节瘤。我们描述了一例大型腹部神经内分泌肿瘤的病例，该肿瘤经活检证实为副神经节瘤。不幸的是，该患者出现高输出心力衰竭，这是副神经节瘤的一种极其罕见的并发症。在进行外科活检之前，患者接受了全面的侵入性和非侵入性心脏检查，以及生化检查。在 PET CT 上，腹膜后神经内分泌肿瘤已转移至脊柱。针对生长抑素类似物的化疗已经开始。本文呈现了该病例的独特表现和罕见并发症，并对相关文献进行了复习，以强调疾病的范围，旨在为诊断和介入放射科医生提供帮助。了解广泛的疾病谱并将其纳入腹膜后肿块的鉴别诊断非常重要。同样重要的是要考虑潜在的并发症，如转移和心力衰竭，以指导适当的检查和管理。
