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关于成人新型冠状病毒肺炎继发急性呼吸衰竭患者无创呼吸支持的临床共识推荐

Clinical Consensus Recommendations Regarding Non-Invasive Respiratory Support in the Adult Patient with Acute Respiratory Failure Secondary to SARS-CoV-2 infection.

作者信息

Cinesi Gómez C, Peñuelas Rodríguez Ó, Luján Torné M L, Egea Santaolalla C, Masa Jiménez J F, García Fernández J, Carratalá Perales J M, Heili-Frades S B, Ferrer Monreal M, de Andrés Nilsson J M, Lista Arias E, Sánchez Rocamora J L, Garrote J I, Zamorano Serrano M J, González Martínez M, Farrero Muñoz E, Mediano San Andrés O, Rialp Cervera G, Mas Serra A, Hernández Martínez G, de Haro López C, Roca Gas O, Ferrer Roca R, Romero Berrocal A, Ferrando Ortola C

机构信息

Dirección General de Asistencia Sanitaria, Servicio Murciano de Salud. Director del Máster Oficial en Medicina de Urgencias y Emergencias, Murcia, España.

Servicio de Medicina Intensiva y Grandes Quemados, Hospital Universitario de Getafe. CIBER de Enfermedades Respiratorias, CIBERES, Getafe, Madrid, España.

出版信息

Rev Esp Anestesiol Reanim (Engl Ed). 2020 May;67(5):261-270. doi: 10.1016/j.redar.2020.03.006. Epub 2020 Apr 16.

DOI:10.1016/j.redar.2020.03.006
PMID:32307151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7161530/
Abstract

Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by a newly emergent coronavirus, that was first recognized in Wuhan, China, in December 2019. Currently, the World Health Organization (WHO) has defined the infection as a global pandemic and there is a health and social emergency for the management of this new infection. While most people with COVID-19 develop only mild or uncomplicated illness, approximately 14% develop severe disease that requires hospitalization and oxygen support, and 5% require admission to an intensive care unit. In severe cases, COVID-19 can be complicated by the acute respiratory distress syndrome (ARDS), sepsis and septic shock, and multiorgan failure. This consensus document has been prepared on evidence-informed guidelines developed by a multidisciplinary panel of health care providers from four Spanish scientific societies (Spanish Society of Intensive Care Medicine [SEMICYUC], Spanish Society of Pulmonologists [SEPAR], Spanish Society of Emergency [SEMES], Spanish Society of Anesthesiology, Reanimation, and Pain [SEDAR]) with experience in the clinical management of patients with COVID-19 and other viral infections, including SARS, as well as sepsis and ARDS. The document provides clinical recommendations for the noninvasive respiratory support (noninvasive ventilation, high flow oxygen therapy with nasal cannula) in any patient with suspected or confirmed presentation of COVID-19 with acute respiratory failure. This consensus guidance should serve as a foundation for optimized supportive care to ensure the best possible chance for survival and to allow for reliable comparison of investigational therapeutic interventions as part of randomized controlled trials.

摘要

2019冠状病毒病(COVID-19)是一种由新出现的冠状病毒引起的呼吸道感染,于2019年12月在中国武汉首次被发现。目前,世界卫生组织(WHO)已将该感染定义为全球大流行,应对这种新感染构成了卫生和社会紧急情况。虽然大多数COVID-19患者仅出现轻症或病情不复杂,但约14%的患者会发展为需要住院和吸氧支持的重症疾病,5%的患者需要入住重症监护病房。在重症病例中,COVID-19可能并发急性呼吸窘迫综合征(ARDS)、脓毒症和脓毒性休克以及多器官功能衰竭。本共识文件是根据由来自四个西班牙科学学会(西班牙重症医学学会[SEMICYUC]、西班牙肺科医师学会[SEPAR]、西班牙急诊学会[SEMES]、西班牙麻醉、复苏与疼痛学会[SEDAR])的多学科医疗保健提供者小组制定的循证指南编写而成,这些提供者在COVID-19及其他病毒感染(包括SARS)以及脓毒症和ARDS患者的临床管理方面具有经验。该文件为任何疑似或确诊患有COVID-19并伴有急性呼吸衰竭的患者提供无创呼吸支持(无创通气、经鼻高流量氧疗)的临床建议。这一共识性指南应作为优化支持治疗的基础,以确保获得最佳生存机会,并便于作为随机对照试验的一部分对研究性治疗干预措施进行可靠比较。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/540f/7161530/d5dc9c2f8234/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/540f/7161530/d5dc9c2f8234/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/540f/7161530/d5dc9c2f8234/gr1_lrg.jpg

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本文引用的文献

1
Potential association between COVID-19 mortality and health-care resource availability.新型冠状病毒肺炎死亡率与医疗资源可及性之间的潜在关联。
Lancet Glob Health. 2020 Apr;8(4):e480. doi: 10.1016/S2214-109X(20)30068-1. Epub 2020 Feb 25.
2
Clinical Characteristics of Coronavirus Disease 2019 in China.《中国 2019 年冠状病毒病临床特征》
N Engl J Med. 2020 Apr 30;382(18):1708-1720. doi: 10.1056/NEJMoa2002032. Epub 2020 Feb 28.
3
Staff safety during emergency airway management for COVID-19 in Hong Kong.香港新冠疫情紧急气道管理期间的医护人员安全
Clinical and organizational opportunities in the management of critical patients in pandemic COVID-19.
2019年冠状病毒病大流行期间危重症患者管理中的临床与组织机遇
Rev Esp Anestesiol Reanim (Engl Ed). 2022 Jun-Jul;69(6):377-378. doi: 10.1016/j.redare.2022.06.005. Epub 2022 Jun 24.
4
Aprotinin treatment against SARS-CoV-2: A randomized phase III study to evaluate the safety and efficacy of a pan-protease inhibitor for moderate COVID-19.抑肽酶治疗 SARS-CoV-2:一项评估泛蛋白酶抑制剂治疗中度 COVID-19 的安全性和有效性的随机 III 期研究。
Eur J Clin Invest. 2022 Jun;52(6):e13776. doi: 10.1111/eci.13776. Epub 2022 Apr 5.
5
[Clinical and organizational opportunities in the management of critical patients in pandemic COVID-19].[新冠疫情期间危重症患者管理中的临床及组织机遇]
Rev Esp Anestesiol Reanim. 2022 Jun-Jul;69(6):377-378. doi: 10.1016/j.redar.2021.06.001. Epub 2021 Nov 12.
6
International expert opinion on the use of nebulization for pediatric asthma therapy during the COVID-19 pandemic.关于在2019冠状病毒病大流行期间雾化吸入用于儿童哮喘治疗的国际专家意见。
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Symptom clusters in COVID-19: A potential clinical prediction tool from the COVID Symptom Study app.COVID-19 症状群:COVID 症状研究应用程序的潜在临床预测工具。
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An Pediatr (Engl Ed). 2021 Feb;94(2):116.e1-116.e11. doi: 10.1016/j.anpede.2020.09.005. Epub 2021 Jan 14.
9
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10
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Am J Emerg Med. 2021 Jan;39:42-47. doi: 10.1016/j.ajem.2020.10.043. Epub 2020 Oct 28.
Lancet Respir Med. 2020 Apr;8(4):e19. doi: 10.1016/S2213-2600(20)30084-9. Epub 2020 Feb 24.
4
Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.中国武汉严重 COVID-19 患者的临床病程和结局:一项单中心、回顾性、观察性研究。
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5
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Intensive Care Med. 2020 Apr;46(4):579-582. doi: 10.1007/s00134-020-05967-x. Epub 2020 Feb 26.
6
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7
[Expert consensus on preventing nosocomial transmission during respiratory care for critically ill patients infected by 2019 novel coronavirus pneumonia].《关于2019新型冠状病毒肺炎感染重症患者呼吸治疗期间预防医院内传播的专家共识》
Zhonghua Jie He He Hu Xi Za Zhi. 2020 Feb 20;17(0):E020. doi: 10.3760/cma.j.issn.1001-0939.2020.0020.
8
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Am J Respir Crit Care Med. 2019 Oct 1;200(7):e45-e67. doi: 10.1164/rccm.201908-1581ST.
9
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Trials. 2019 Jul 22;20(1):450. doi: 10.1186/s13063-019-3514-1.
10
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Int J Chron Obstruct Pulmon Dis. 2019 Jun 5;14:1229-1237. doi: 10.2147/COPD.S206567. eCollection 2019.