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[关于新型冠状病毒肺炎继发急性呼吸衰竭成年患者无创呼吸支持的临床共识推荐意见]

[Clinical Consensus Recommendations Regarding Non-Invasive Respiratory Support in the Adult Patient with Acute Respiratory Failure Secondary to SARS-CoV-2 infection].

作者信息

Cinesi Gómez César, Peñuelas Rodríguez Óscar, Luján Torné Manel, Egea Santaolalla Carlos, Masa Jiménez Juan Fernando, García Fernández Javier, Carratalá Perales José Manuel, Heili-Frades Sarah Béatrice, Ferrer Monreal Miquel, de Andrés Nilsson José M, Lista Arias Eva, Sánchez Rocamora Juan Luis, Garrote José Ignacio, Zamorano Serrano Miguel J, González Martínez Mónica, Farrero Muñoz Eva, Mediano San Andrés Olga, Rialp Cervera Gemma, Mas Serra Arantxa, Hernández Martínez Gonzalo, de Haro López Candelaria, Roca Gas Oriol, Ferrer Roca Ricard, Romero Berrocal Antonio, Ferrando Ortola Carlos

机构信息

Dirección General de Asistencia Sanitaria, Servicio Murciano de Salud. Director del Máster Oficial en Medicina de Urgencias y Emergencias, Murcia, España.

Servicio de Medicina Intensiva y Grandes Quemados, Hospital Universitario de Getafe. CIBER de Enfermedades Respiratorias, CIBERES, Getafe, Madrid, España.

出版信息

Arch Bronconeumol. 2020 Jul;56:11-18. doi: 10.1016/j.arbres.2020.03.005. Epub 2020 Mar 30.

DOI:10.1016/j.arbres.2020.03.005
PMID:34629620
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7270645/
Abstract

Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by a newly emergent coronavirus, that was first recognized in Wuhan, China, in December 2019. Currently, the World Health Organization (WHO) has defined the infection as a global pandemic and there is a health and social emergency for the management of this new infection. While most people with COVID-19 develop only mild or uncomplicated illness, approximately 14% develop severe disease that requires hospitalization and oxygen support, and 5% require admission to an intensive care unit. In severe cases, COVID-19 can be complicated by the acute respiratory distress syndrome (ARDS), sepsis and septic shock, and multiorgan failure. This consensus document has been prepared on evidence-informed guidelines developed by a multidisciplinary panel of health care providers from four Spanish scientific societies ( [SEMICYUC], [SEPAR], [SEMES], [SEDAR]) with experience in the clinical management of patients with COVID-19 and other viral infections, including SARS, as well as sepsis and ARDS. The document provides clinical recommendations for the noninvasive respiratory support (noninvasive ventilation, high flow oxygen therapy with nasal cannula) in any patient with suspected or confirmed presentation of COVID-19 with acute respiratory failure.This consensus guidance should serve as a foundation for optimized supportive care to ensure the best possible chance for survival and to allow for reliable comparison of investigational therapeutic interventions as part of randomized controlled trials.

摘要

2019冠状病毒病(COVID-19)是一种由新出现的冠状病毒引起的呼吸道感染,该病毒于2019年12月在中国武汉首次被发现。目前,世界卫生组织(WHO)已将该感染定义为全球大流行,应对这种新感染构成了一项卫生和社会紧急情况。虽然大多数COVID-19患者仅出现轻症或无并发症的疾病,但约14%的患者会发展为需要住院和吸氧支持的重症疾病,5%的患者需要入住重症监护病房。在重症病例中,COVID-19可能并发急性呼吸窘迫综合征(ARDS)、脓毒症和脓毒性休克以及多器官功能衰竭。本共识文件是根据来自四个西班牙科学学会([SEMICYUC]、[SEPAR]、[SEMES]、[SEDAR])的多学科医疗保健提供者小组制定的循证指南编写而成,这些提供者在COVID-19和其他病毒感染(包括SARS)以及脓毒症和ARDS的临床管理方面具有经验。该文件为任何疑似或确诊患有COVID-19并伴有急性呼吸衰竭的患者提供无创呼吸支持(无创通气、经鼻高流量氧疗)的临床建议。本共识指南应作为优化支持治疗的基础,以确保获得最佳生存机会,并允许作为随机对照试验一部分的研究性治疗干预措施进行可靠比较。

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Clinical Characteristics of Coronavirus Disease 2019 in China.《中国 2019 年冠状病毒病临床特征》
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