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用左旋咪唑治疗皮肤结节病。

Cutaneous sarcoidosis treated with levamisole.

作者信息

Veien N K

出版信息

Dermatologica. 1977;154(3):185-9. doi: 10.1159/000251128.

Abstract

16 patients with cutaneous sarcoidosis were treated intermittently over a period of 6 months with levamisole in an open study. The skin lesions cleared in 2 of 13 patients completing the course of treatment. Aggravation of the sarcoidosis was noted in 2 other patients after a few weeks of treatment. Tuberculin sensitivity did not increase during the treatment period. Dinitrochlorobenzene sensitivity increased in 5 patients but the lesions did not clear in any of these patients. It is concluded that levamisole is not useful in the treatment of cutaneous sarcoidosis.

摘要

在一项开放性研究中,16例皮肤结节病患者接受了为期6个月的左旋咪唑间歇性治疗。13例完成治疗疗程的患者中,有2例皮肤病变消退。另外2例患者在治疗几周后结节病加重。治疗期间结核菌素敏感性未增加。5例患者二硝基氯苯敏感性增加,但这些患者中无一例病变消退。结论是左旋咪唑对皮肤结节病治疗无效。

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