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格鲁吉亚的孕产妇死亡率:发病率、原因及报告不足程度:2014年全国生育年龄死亡率研究

Maternal Mortality in Georgia: Incidence, Causes and Level of Underreporting: A National Reproductive Age Mortality Study 2014.

作者信息

Berdzuli Nino, Lomia Nino, Staff Anne Cathrine, Kereselidze Maia, Lazdane Gunta, Jacobsen Anne Flem

机构信息

Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.

Division of Obstetrics and Gynaecology, Oslo University Hospital, Oslo, Norway.

出版信息

Int J Womens Health. 2020 Apr 9;12:277-286. doi: 10.2147/IJWH.S227349. eCollection 2020.

Abstract

INTRODUCTION

Accurate data on maternal mortality are essential for assessing progress towards Sustainable Development Goals (SDG).The aim of the study was to determine the incidence and causes of maternal deaths in Georgia, then explore the potential for improvement of quality of maternal health care. The study's secondary aims were to identify the level of underreporting of maternal deaths in Georgian vital statistics over 1 year (2012) and to compare these results with previous data from 2006. The study findings allow to support the country in developing evidence-based policies and tracking progress towards meeting SDG targets.

METHODS

A national Reproductive Age Mortality Survey (RAMOS) was conducted in Georgia in 2014-15. Multiple data sources were used to identify deaths of women aged 15-49 years between January and December 2012. All deaths in women of reproductive age were investigated through verbal autopsy (VA) diagnoses. Deaths in women during pregnancy or one-year postpartum were further investigated by conducting interviews and medical record reviews at the last medical facility which provided health care for the woman during her fatal condition. A specialist panel reviewed these cases and assigned underlining causes of deaths.

RESULTS

We found that 98% of deaths among women of reproductive age were registered by Georgia's civil registration and vital statistics system (CRVS). A total of 918 deaths met the study inclusion criteria. Thirty-six (4.1%) women died during pregnancy or within one-year postpartum. Among these 36 deaths, 23 (63.8%) were maternal deaths, 15 early (either during pregnancy or 42 days postpartum) and eight late (43-365 days postpartum) deaths (65.2% vs 34.8%). The remaining 13 of 36 deaths were coincidental deaths. Fourteen maternal deaths were reported by official statistics and nine deaths were not included in these statistics. Thus, the underreporting rate was 39%. Direct obstetric causes accounted for 73.9% (n=17) of maternal deaths, whereas 26.1% (n=6) were indirect. The leading causes of direct maternal deaths were infection (21.7%), hemorrhage (17.4%), pulmonary embolism (13.0%), and pregnancy-induced hypertension (8.7%). The RAMOS study calculated a maternal mortality ratio (early maternal deaths) of 26.3 per 100,000 live births compared with the official figure of 22.8 per 100,000 live births.

DISCUSSIONS

Registration of early maternal deaths significantly improved since last survey in 2008, while indirect and late maternal deaths continue to be unrecognized, as reflected in official Georgian statistics. The difference between RAMOS study findings and officially reported maternal mortality rates is minimal, showing improvements in detection of maternal deaths by the national maternal mortality surveillance system. The greatest number of direct obstetric deaths occur in the first week postpartum, which likely reflects deficiencies in quality of care.

摘要

引言

准确的孕产妇死亡率数据对于评估可持续发展目标(SDG)的进展至关重要。本研究的目的是确定格鲁吉亚孕产妇死亡的发生率和原因,进而探索改善孕产妇保健质量的潜力。该研究的次要目的是确定格鲁吉亚生命统计数据中1年(2012年)内孕产妇死亡漏报的程度,并将这些结果与2006年的先前数据进行比较。研究结果有助于支持该国制定循证政策并跟踪实现可持续发展目标指标的进展情况。

方法

2014年至2015年在格鲁吉亚进行了一项全国生殖年龄死亡率调查(RAMOS)。使用了多个数据源来识别2012年1月至12月期间15至49岁女性的死亡情况。通过口头尸检(VA)诊断对所有育龄妇女的死亡进行了调查。对怀孕或产后一年内死亡的妇女,在其病情危急时为其提供医疗服务的最后一家医疗机构进行访谈和病历审查,作进一步调查。一个专家小组对这些病例进行了审查,并确定了死亡的根本原因。

结果

我们发现,格鲁吉亚的民事登记和生命统计系统(CRVS)登记了98%的育龄妇女死亡情况。共有918例死亡符合研究纳入标准。36名(4.1%)妇女在怀孕期间或产后一年内死亡。在这36例死亡中,23例(63.8%)为孕产妇死亡,其中15例为早期死亡(孕期或产后42天内),8例为晚期死亡(产后43 - 365天)(65.2%对34.8%)。36例死亡中的其余13例为偶合死亡。官方统计报告了14例孕产妇死亡,另有9例死亡未纳入这些统计数据。因此,漏报率为39%。直接产科原因占孕产妇死亡的73.9%(n = 17),而间接原因占26.1%(n = 6)。直接孕产妇死亡的主要原因是感染(21.7%)、出血(17.4%)、肺栓塞(13.0%)和妊娠高血压(8.7%)。RAMOS研究计算出的孕产妇死亡率(早期孕产妇死亡)为每10万活产26.3例,而官方数字为每10万活产22.8例。

讨论

自2008年上次调查以来,早期孕产妇死亡的登记情况有了显著改善,但格鲁吉亚官方统计数据显示,间接和晚期孕产妇死亡仍未得到确认。RAMOS研究结果与官方报告的孕产妇死亡率之间的差异很小,表明国家孕产妇死亡率监测系统在孕产妇死亡检测方面有所改进。最大数量的直接产科死亡发生在产后第一周,这可能反映了护理质量的不足。

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