用于医疗保健应用的智能合约区块链比较
Comparison of Smart Contract Blockchains for Healthcare Applications.
作者信息
Yu Hongru, Sun Haiyang, Wu Danyi, Kuo Tsung-Ting
机构信息
University of California San Diego, La Jolla, CA, USA.
Contributed Equally.
出版信息
AMIA Annu Symp Proc. 2020 Mar 4;2019:1266-1275. eCollection 2019.
Abstract
Blockchain and smart contracts (i.e., computer code that can be run on blockchain) are increasingly popular for healthcare applications. However, only very few implementations exist because of the complexity of the technologies. Although there are tutorials and reviews to introduce blockchain and smart contracts, a pragmatic comparison of such platforms is needed. In this study, we addressed practical considerations while building a healthcare blockchain and smart contract system, by (1) comparing technical features of platforms, (2) selecting three platforms, (3) constructing blockchain networks, (4) testing the blockchains, and (5) summarizing the experience and time used for implementation by students. We evaluated Ethereum, Hyperledger Fabric, and MultiChain, and confirmed that the selection of a proper platform depends on the requirements of the application. The findings of our study can accelerate the process and reduce the risk of adopting blockchain technology in biomedical and healthcare domain.
摘要
区块链和智能合约（即可以在区块链上运行的计算机代码）在医疗保健应用中越来越受欢迎。然而，由于技术的复杂性，只有极少数的应用实例。尽管有教程和综述来介绍区块链和智能合约，但仍需要对这些平台进行务实的比较。在本研究中，我们通过以下方式在构建医疗区块链和智能合约系统时考虑实际因素：（1）比较平台的技术特性；（2）选择三个平台；（3）构建区块链网络；（4）测试区块链；（5）总结学生实施过程中的经验和所用时间。我们评估了以太坊、超级账本织物和多链，并确认选择合适的平台取决于应用的需求。我们的研究结果可以加快在生物医学和医疗领域采用区块链技术的进程并降低风险。
相似文献
1
Comparison of Smart Contract Blockchains for Healthcare Applications.用于医疗保健应用的智能合约区块链比较
AMIA Annu Symp Proc. 2020 Mar 4;2019:1266-1275. eCollection 2019.
2
Automatic Recommender System of Development Platforms for Smart Contract-Based Health Care Insurance Fraud Detection Solutions: Taxonomy and Performance Evaluation.基于智能合约的医疗保险欺诈检测解决方案的开发平台自动推荐系统：分类法与性能评估。
J Med Internet Res. 2024 Oct 18;26:e50730. doi: 10.2196/50730.
3
Comparison of blockchain platforms: a systematic review and healthcare examples.区块链平台比较：系统评价及医疗保健实例。
J Am Med Inform Assoc. 2019 May 1;26(5):462-478. doi: 10.1093/jamia/ocy185.
4
A Systematic Comparison between the Ethereum and Hyperledger Fabric Blockchain Platforms for Attribute-Based Access Control in Smart Home IoT Environments.以太坊与超级账本织物区块链平台在智能家居物联网环境中基于属性的访问控制方面的系统比较
Sensors (Basel). 2023 Aug 9;23(16):7046. doi: 10.3390/s23167046.
5
Geospatial blockchain: promises, challenges, and scenarios in health and healthcare.地理空间区块链：在健康和医疗保健中的承诺、挑战和场景。
Int J Health Geogr. 2018 Jul 5;17(1):25. doi: 10.1186/s12942-018-0144-x.
6
Using Ethereum blockchain to store and query pharmacogenomics data via smart contracts.利用以太坊区块链通过智能合约存储和查询药物基因组学数据。
BMC Med Genomics. 2020 Jun 1;13(1):74. doi: 10.1186/s12920-020-00732-x.
7
Blockchain Integration With Digital Technology and the Future of Health Care Ecosystems: Systematic Review.区块链与数字技术融合与医疗保健生态系统的未来：系统评价。
J Med Internet Res. 2021 Nov 2;23(11):e19846. doi: 10.2196/19846.
8
Improving Diagnosis Through Digital Pathology: Proof-of-Concept Implementation Using Smart Contracts and Decentralized File Storage.通过数字病理学改善诊断：使用智能合约和去中心化文件存储实现概念验证。
J Med Internet Res. 2022 Mar 28;24(3):e34207. doi: 10.2196/34207.
9
Towards a Remote Monitoring of Patient Vital Signs Based on IoT-Based Blockchain Integrity Management Platforms in Smart Hospitals.迈向基于智能医院中基于物联网的区块链完整性管理平台的患者生命体征远程监测。
Sensors (Basel). 2020 Apr 13;20(8):2195. doi: 10.3390/s20082195.
10
Possible Usages of Smart Contracts (Blockchain) in Healthcare and Why No One Is Using Them.智能合约（区块链）在医疗保健领域的可能用途以及为何无人使用它们。
Stud Health Technol Inform. 2019 Aug 21;264:596-600. doi: 10.3233/SHTI190292.
引用本文的文献
1
Distributed cross-learning for equitable federated models - privacy-preserving prediction on data from five California hospitals.用于公平联邦模型的分布式交叉学习——对来自加利福尼亚州五家医院的数据进行隐私保护预测。
Nat Commun. 2025 Feb 5;16(1):1371. doi: 10.1038/s41467-025-56510-9.
2
Distributed, immutable, and transparent biomedical limited data set request management on multi-capacity network.多容量网络上的分布式、不可变且透明的生物医学有限数据集请求管理
J Am Med Inform Assoc. 2025 Feb 1;32(2):296-307. doi: 10.1093/jamia/ocae288.
3
WebQuorumChain: A web framework for quorum-based health care model learning.WebQuorumChain：一种用于基于仲裁的医疗保健模型学习的网络框架。
Inform Med Unlocked. 2024;50. doi: 10.1016/j.imu.2024.101590. Epub 2024 Oct 11.
4
Distributed management of patient data-sharing informed consents for clinical research.患者数据共享知情同意的分布式管理用于临床研究。
Comput Biol Med. 2024 Sep;180:108956. doi: 10.1016/j.compbiomed.2024.108956. Epub 2024 Aug 8.
5
Biomedical blockchain with practical implementations and quantitative evaluations: a systematic review.具有实际应用和定量评估的生物医学区块链：系统评价。
J Am Med Inform Assoc. 2024 May 20;31(6):1423-1435. doi: 10.1093/jamia/ocae084.
6
A blockchain-based healthcare data marketplace: prototype and demonstration.基于区块链的医疗数据市场：原型与演示。
JAMIA Open. 2024 Apr 12;7(2):ooae029. doi: 10.1093/jamiaopen/ooae029. eCollection 2024 Jul.
7
Web3-based storage solutions for biomedical research and clinical data exchange.用于生物医学研究和临床数据交换的基于Web3的存储解决方案。
J Am Med Inform Assoc. 2024 Feb 16;31(3):790-793. doi: 10.1093/jamia/ocad227.
8
The Hyperledger fabric as a Blockchain framework preserves the security of electronic health records.超级账本架构作为区块链框架，保障电子健康记录的安全性。
Front Public Health. 2023 Nov 28;11:1272787. doi: 10.3389/fpubh.2023.1272787. eCollection 2023.
9
Case studies about smart contracts in healthcare.医疗保健领域智能合约的案例研究。
Digit Health. 2023 Oct 8;9:20552076231203571. doi: 10.1177/20552076231203571. eCollection 2023 Jan-Dec.
10
Blockchain-enabled immutable, distributed, and highly available clinical research activity logging system for federated COVID-19 data analysis from multiple institutions.区块链赋能的不可变、分布式、高可用的临床研究活动日志系统，用于从多个机构进行联邦 COVID-19 数据分析。
J Am Med Inform Assoc. 2023 May 19;30(6):1167-1178. doi: 10.1093/jamia/ocad049.
本文引用的文献
1
EXpectation Propagation LOgistic REgRession on permissioned blockCHAIN (ExplorerChain): decentralized online healthcare/genomics predictive model learning.许可区块链上的期望传播逻辑回归（ExplorerChain）：去中心化在线医疗保健/基因组学预测模型学习。
J Am Med Inform Assoc. 2020 May 1;27(5):747-756. doi: 10.1093/jamia/ocaa023.
2
'Fit-for-purpose?' - challenges and opportunities for applications of blockchain technology in the future of healthcare.“合适用途？”——区块链技术在未来医疗保健中的应用面临的挑战和机遇。
BMC Med. 2019 Mar 27;17(1):68. doi: 10.1186/s12916-019-1296-7.
3
Comparison of blockchain platforms: a systematic review and healthcare examples.区块链平台比较：系统评价及医疗保健实例。
J Am Med Inform Assoc. 2019 May 1;26(5):462-478. doi: 10.1093/jamia/ocy185.
4
Fair compute loads enabled by blockchain: sharing models by alternating client and server roles.通过区块链实现公平的计算负载：通过交替客户端和服务器角色来共享模型。
J Am Med Inform Assoc. 2019 May 1;26(5):392-403. doi: 10.1093/jamia/ocy180.
5
FHIRChain: Applying Blockchain to Securely and Scalably Share Clinical Data.FHIRChain：应用区块链安全且可扩展地共享临床数据。
Comput Struct Biotechnol J. 2018 Jul 29;16:267-278. doi: 10.1016/j.csbj.2018.07.004. eCollection 2018.
6
Healthcare Blockchain System Using Smart Contracts for Secure Automated Remote Patient Monitoring.使用智能合约的医疗保健区块链系统，用于安全的自动化远程患者监测。
J Med Syst. 2018 Jun 6;42(7):130. doi: 10.1007/s10916-018-0982-x.
7
Secure and Trustable Electronic Medical Records Sharing using Blockchain.利用区块链实现安全可信的电子病历共享
AMIA Annu Symp Proc. 2018 Apr 16;2017:650-659. eCollection 2017.
8
Blockchain distributed ledger technologies for biomedical and health care applications.用于生物医学和医疗保健应用的区块链分布式账本技术。
J Am Med Inform Assoc. 2017 Nov 1;24(6):1211-1220. doi: 10.1093/jamia/ocx068.
9
Where Is Current Research on Blockchain Technology?-A Systematic Review.区块链技术的当前研究现状如何？——一项系统综述。
PLoS One. 2016 Oct 3;11(10):e0163477. doi: 10.1371/journal.pone.0163477. eCollection 2016.
10
Healthcare Data Gateways: Found Healthcare Intelligence on Blockchain with Novel Privacy Risk Control.医疗保健数据网关：在区块链上发现具有新颖隐私风险控制的医疗保健情报。
J Med Syst. 2016 Oct;40(10):218. doi: 10.1007/s10916-016-0574-6. Epub 2016 Aug 26.
Zotero 插件