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将剖宫产术后阴道分娩预测模型应用于拉丁裔市中心人群。

Applying a Prediction Model for Vaginal Birth after Cesarean to a Latina Inner-City Population.

作者信息

Nguyen Michelle T, Hayes-Bautista Teodocia Maria, Hsu Paul, Bragg Christina, Chopin Irving, Shaw Kathryn J

机构信息

Department of Obstetrics and Gynecology, Adventist Health White Memorial Medical Center, Los Angeles, California.

Department of Graduate Medical Education, Adventist Health White Memorial Medical Center, Los Angeles, California.

出版信息

AJP Rep. 2020 Apr;10(2):e148-e154. doi: 10.1055/s-0040-1708493. Epub 2020 Apr 15.

DOI:10.1055/s-0040-1708493
PMID:32309016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7159979/
Abstract

The Maternal-Fetal Medicine Units (MFMU) Network developed a prediction model for calculating the likelihood of successful vaginal birth after cesarean (VBAC) in patients undergoing a trial of labor after cesarean (TOLAC). In this prediction model, Latina ethnicity is considered a negative predictive factor for successful VBAC. Subsequent studies have found mixed results regarding VBAC success in Latina ethnicity.  Our aim was to compare the predicted chance of successful VBAC (as calculated using the MFMU prediction model) to actual TOLAC outcomes in a large Latina sample.  We performed a retrospective cohort study of Latinas who underwent TOLAC at our institution from January 1, 2013 to December 31, 2016. The MFMU prediction model was used to calculate each participant's predicted success, and the participants were then categorized into three groups based on predicted success: low (<35%), moderate (35-65%), and high (>65%). The predicted success rates versus actual outcomes were compared among the three groups.  A total of 567 Latinas met inclusion criteria. Successful VBAC occurred in 476 patients (84%). VBAC was achieved in 65.3% of the low predicted success group, 84.4% of the moderate predicted success group, and 91.7% of the predicted high success group. Actual VBAC success rates exceeded the predicted success rates for the low and moderate groups.  Our results question whether Latina ethnicity should continue to be considered a negative predictive factor for VBAC success. Our results also suggest that Latinas with a low predicted VBAC success should not necessarily be discouraged from attempting TOLAC.

摘要

母胎医学单位(MFMU)网络开发了一种预测模型,用于计算剖宫产术后试产(TOLAC)患者成功阴道分娩(VBAC)的可能性。在这个预测模型中,拉丁裔被认为是VBAC成功的一个负面预测因素。随后的研究发现,关于拉丁裔VBAC成功的结果不一。我们的目的是在一个大型拉丁裔样本中,比较预测的VBAC成功机会(使用MFMU预测模型计算)与实际的TOLAC结果。我们对2013年1月1日至2016年12月31日在我们机构接受TOLAC的拉丁裔进行了一项回顾性队列研究。使用MFMU预测模型计算每个参与者的预测成功率,然后根据预测成功率将参与者分为三组:低(<35%)、中(35-65%)和高(>65%)。比较三组的预测成功率与实际结果。共有567名拉丁裔符合纳入标准。476名患者(84%)成功实现VBAC。在预测成功率低的组中,VBAC成功率为65.3%,在预测成功率中等的组中为84.4%,在预测成功率高的组中为91.7%。低和中等组的实际VBAC成功率超过了预测成功率。我们的结果质疑拉丁裔是否应继续被视为VBAC成功的负面预测因素。我们的结果还表明,预测VBAC成功率低的拉丁裔不一定应被劝阻尝试TOLAC。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01ce/7159979/a0862d77d778/10-1055-s-0040-1708493-i200002-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01ce/7159979/a0862d77d778/10-1055-s-0040-1708493-i200002-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01ce/7159979/a0862d77d778/10-1055-s-0040-1708493-i200002-1.jpg

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本文引用的文献

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Race, Research, and Women's Health: Best Practice Guidelines for Investigators.种族、研究与妇女健康:研究人员最佳实践指南。
Obstet Gynecol. 2019 Apr;133(4):815-818. doi: 10.1097/AOG.0000000000003157.
2
Practice Bulletin No. 184: Vaginal Birth After Cesarean Delivery.实践公告第 184 号:剖宫产术后阴道分娩。
Obstet Gynecol. 2017 Nov;130(5):e217-e233. doi: 10.1097/AOG.0000000000002398.
3
Validation of a Prediction Model for Vaginal Birth after Cesarean Delivery Reveals Unexpected Success in a Diverse American Population.
剖宫产术后阴道分娩预测模型的验证显示,该模型在多样化的美国人群中取得了意想不到的成功。
AJP Rep. 2017 Jan;7(1):e31-e38. doi: 10.1055/s-0037-1599129.
4
Do Obese Women Receive the Necessary Interventions to Achieve Vaginal Birth after Cesarean?肥胖女性是否接受了必要的干预措施以实现剖宫产术后阴道分娩?
Am J Perinatol. 2016 Aug;33(10):991-7. doi: 10.1055/s-0036-1580609. Epub 2016 Apr 27.
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Validation of a vaginal birth after cesarean delivery prediction model in women with two prior cesarean deliveries.经剖宫产分娩预测模型在有两次既往剖宫产史女性中的验证
Obstet Gynecol. 2015 Apr;125(4):948-952. doi: 10.1097/AOG.0000000000000744.
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Safe prevention of the primary cesarean delivery.安全预防初次剖宫产。
Am J Obstet Gynecol. 2014 Mar;210(3):179-93. doi: 10.1016/j.ajog.2014.01.026.
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Predictors of failed trial of labor among women with an extremely obese body mass index.极度肥胖女性试产失败的预测因素。
Am J Obstet Gynecol. 2013 Dec;209(6):562.e1-5. doi: 10.1016/j.ajog.2013.07.023. Epub 2013 Jul 24.
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Intrapartum management of category II fetal heart rate tracings: towards standardization of care.产时类别 II 胎心监护图的管理:走向规范化护理。
Am J Obstet Gynecol. 2013 Aug;209(2):89-97. doi: 10.1016/j.ajog.2013.04.030. Epub 2013 Apr 27.
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Does information available at admission for delivery improve prediction of vaginal birth after cesarean?入院时可获得的信息是否能提高剖宫产术后阴道分娩的预测准确性?
Am J Perinatol. 2009 Nov;26(10):693-701. doi: 10.1055/s-0029-1239494. Epub 2009 Oct 7.
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Development of a nomogram for prediction of vaginal birth after cesarean delivery.剖宫产术后阴道分娩预测列线图的开发。
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