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小容量医疗中心A型主动脉夹层的手术结果:根据手术范围进行分析。

Surgical Outcomes of Type A Aortic Dissection at a Small-Volume Medical Center: Analysis according to the Extent of Surgery.

作者信息

Lee Chul Ho, Cho Jun Woo, Jang Jae Seok, Yoon Tae Hong

机构信息

Department of Thoracic and Cardiovascular Surgery, School of Medicine, Catholic University of Daegu, Daegu, Korea.

出版信息

Korean J Thorac Cardiovasc Surg. 2020 Apr 5;53(2):58-63. doi: 10.5090/kjtcs.2020.53.2.58.

DOI:10.5090/kjtcs.2020.53.2.58
PMID:32309204
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7155175/
Abstract

BACKGROUND

Despite progress in treatment, Stanford type A aortic dissection is still a life-threatening disease. In this study, we analyzed surgical outcomes in patients with Stanford type A aortic dissection according to the extent of surgery at Daegu Catholic University Medical Center.

METHODS

We retrospectively analyzed 98 patients with Stanford type A aortic dissection who underwent surgery at our institution between January 2008 and June 2018. Of these patients, 82 underwent limited replacement (hemi-arch or ascending aortic replacement), while 16 patients underwent total arch replacement (TAR). We analyzed in-hospital mortality, postoperative complications, the overall 5-year survival rate, and the 5-year aortic event-free survival rate.

RESULTS

The median follow-up time was 48 months (range, 1-128 months), with a completion rate of 85.7% (n=84). The overall in-hospital mortality rate was 8.2%: 6.1% in the limited replacement group and 18.8% in the TAR group (p=0.120). The overall 5-year survival rate was 78.8% in the limited replacement group and 81.3% in the TAR group (p=0.78). The overall 5-year aortic event-free survival rate was 85.3% in the limited replacement group and 88.9% in the TAR group (p=0.46).

CONCLUSION

The extent of surgery was not related to the rates of in-hospital mortality, complications, aortic events, or survival. Although this study was conducted at a small-volume center, the in-hospital mortality and 5-year survival rates were satisfactory.

摘要

背景

尽管在治疗方面取得了进展,但 Stanford A 型主动脉夹层仍然是一种危及生命的疾病。在本研究中,我们根据大邱天主教大学医学中心的手术范围分析了 Stanford A 型主动脉夹层患者的手术结果。

方法

我们回顾性分析了 2008 年 1 月至 2018 年 6 月在我院接受手术的 98 例 Stanford A 型主动脉夹层患者。其中,82 例接受了有限置换(半弓或升主动脉置换),而 16 例患者接受了全弓置换(TAR)。我们分析了住院死亡率、术后并发症、总体 5 年生存率和 5 年无主动脉事件生存率。

结果

中位随访时间为 48 个月(范围 1 - 128 个月),完成率为 85.7%(n = 84)。总体住院死亡率为 8.2%:有限置换组为 6.1%,TAR 组为 18.8%(p = 0.120)。有限置换组的总体 5 年生存率为 78.8%,TAR 组为 81.3%(p = 0.78)。有限置换组的总体 5 年无主动脉事件生存率为 85.3%,TAR 组为 88.9%(p = 0.46)。

结论

手术范围与住院死亡率、并发症、主动脉事件或生存率无关。尽管本研究是在一个小容量中心进行的,但住院死亡率和 5 年生存率令人满意。

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本文引用的文献

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Int J Cardiol. 2018 Sep 15;267:145-149. doi: 10.1016/j.ijcard.2018.05.111. Epub 2018 May 30.
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Limited root repair in acute type A aortic dissection is safe but results in increased risk of reoperation.急性 A 型主动脉夹层行局限性根部修复术安全,但会增加再次手术的风险。
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Can preoperative neutrophil-to-lymphocyte ratio predict in-hospital mortality in postoperative patients with Stanford type A aortic dissection? Evidence-based appraisal by meta-analysis and GRADE.术前中性粒细胞与淋巴细胞比值能否预测 Stanford A 型主动脉夹层术后患者的院内死亡率?基于 Meta 分析和 GRADE 的循证评估
Tzu Chi Med J. 2021 Apr 5;33(4):388-394. doi: 10.4103/tcmj.tcmj_249_20. eCollection 2021 Oct-Dec.
升主动脉弓部替换的范围:全弓置换与窦部+象鼻支架植入。
Eur J Cardiothorac Surg. 2017 Dec 1;52(6):1104-1110. doi: 10.1093/ejcts/ezx214.
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Acute type A aortic dissection in the United Kingdom: Surgeon volume-outcome relation.英国急性 A 型主动脉夹层:外科医生手术量-效果关系。
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