Aomura Daiki, Sonoda Kosuke, Harada Makoto, Hashimoto Koji, Kamijo Yuji
Department of Nephrology, Shinshu University School of Medicine, Matsumoto, Japan.
Case Rep Nephrol Dial. 2020 Mar 30;10(1):26-34. doi: 10.1159/000506673. eCollection 2020 Jan-Apr.
Exercise-induced acute kidney injury (EIAKI) frequently develops in patients with renal hypouricemia (RHUC). However, several cases of RHUC with acute kidney injury (AKI) but without intense exercise have been reported. We encountered a 15-year-old male with RHUC who experienced AKI. He reported no episodes of intense exercise and displayed no other representative risk factors of EIAKI, although a vasopressor had been administered for orthostatic dysregulation before AKI onset. His kidney dysfunction improved with discontinuation of the vasopressor and conservative treatment. Thus, AKI can develop in patients with RHUC in the absence of intense exercise, for which vasopressors may be a risk factor.
运动诱发的急性肾损伤（EIAKI）在肾性低尿酸血症（RHUC）患者中经常发生。然而，已有几例报告称，患有急性肾损伤（AKI）的RHUC患者未进行剧烈运动。我们遇到一名患有RHUC且发生AKI的15岁男性。他报告没有剧烈运动史，也没有EIAKI的其他典型危险因素，尽管在AKI发作前曾使用血管升压药治疗体位性调节障碍。停用血管升压药并进行保守治疗后，他的肾功能障碍有所改善。因此，RHUC患者在没有剧烈运动的情况下也可能发生AKI，血管升压药可能是其中一个危险因素。
