代谢和减重手术后心血管风险的降低
Cardiovascular risk reduction following metabolic and bariatric surgery.
作者信息
English Wayne J, Spann Matthew D, Aher Chetan V, Williams D Brandon
机构信息
Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
出版信息
Ann Transl Med. 2020 Mar;8(Suppl 1):S12. doi: 10.21037/atm.2020.01.88.
Abstract
Cardiovascular disease (CVD) is the world's leading cause of mortality and obesity is a well-recognized risk factor of CVD. Early detection and management of CVD is critical to reduce CVD risk. Especially in patients suffering from obesity with obesity-related CVD risk factors such as hypertension (HTN), dyslipidemia, and diabetes mellitus (DM). A substantial and sustained decrease in body weight after metabolic and bariatric surgery is associated with a significant reduction of cardiovascular risk factors. This article reviews CVD risk models, mechanisms of CVD risk associated with obesity, and overall CVD risk reduction between different metabolic and bariatric procedures.
摘要
心血管疾病（CVD）是全球首要死因，肥胖是公认的心血管疾病风险因素。早期发现和管理心血管疾病对于降低心血管疾病风险至关重要。尤其是对于患有肥胖症且伴有肥胖相关心血管疾病风险因素（如高血压（HTN）、血脂异常和糖尿病（DM））的患者。代谢和减重手术后体重显著且持续下降与心血管风险因素显著降低相关。本文综述了心血管疾病风险模型、与肥胖相关的心血管疾病风险机制以及不同代谢和减重手术之间总体心血管疾病风险的降低情况。
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