Ryu Won Hyung A, Platt Andrew, Deutsch Harel
Department of Neurological Surgery, Rush University, Chicago, IL, USA.
Section of Neurosurgery, University of Chicago, Chicago, IL, USA.
J Spine Surg. 2020 Mar;6(1):181-195. doi: 10.21037/jss.2019.12.08.
The primary treatment of choice for patients with cervical spondylotic myelopathy (CSM) is surgical decompression. The benefit of operative intervention has been well established but, the surgeons' decision of operative approach remains nuanced based on patient-specific variables and surgeon preference. Decompression can involve a cervical corpectomy or a discectomy. A hybrid construct is when both a cervical corpectomy and a discectomy are done in the same patient. The purpose of this study was to review the evidence on the clinical and biomechanical outcomes of hybrid decompression and reconstruction techniques in patients with multilevel CSM. A retrospective study was performed on consecutive patients who received hybrid anterior decompression and reconstruction at Rush University between 2013-2018. Preoperative clinical and radiographic variables were analyzed to characterize specific factors leading to the decision of the surgical approach. In addition, we performed a systematic review and meta-analysis to assess superiority in terms of operative time, blood loss, cervical lordosis, patient-reported outcomes (PRO), fusion rates, and complications. Hybrid surgery (HS) was utilized in cases where multilevel CSM was present in conjunction with stenosis posterior to the vertebral body or acute kyphotic deformity. Our meta-analysis highlighted comparable PRO, complications, and rate of success fusion between 3-level anterior cervical discectomy and fusion (ACDF) and hybrid technique. Furthermore, hybrid fusion led to increased postoperative cervical lordosis, higher fusion rate, lower total complication rate, lower implant failure/mesh subsidence rate, and lower blood loss than 2-level corpectomy. The cervical hybrid technique that combines cervical corpectomy and discectomy represents a balanced option with the benefits of two commonly utilized cervical spine procedures in patients with multilevel CSM. The literature on hybrid technique suggests in cases where multilevel ACDF is not feasible, combining discectomy and corpectomy is superior to two-level corpectomy with lower complication rates, improved clinical outcome, spinal alignment correction, and stronger biomechanical properties.
脊髓型颈椎病(CSM)患者的主要治疗选择是手术减压。手术干预的益处已得到充分证实,但外科医生对手术入路的决策仍因患者的具体变量和外科医生的偏好而存在细微差别。减压可包括颈椎椎体次全切除术或椎间盘切除术。混合术式是指在同一患者身上同时进行颈椎椎体次全切除术和椎间盘切除术。本研究的目的是回顾关于混合减压与重建技术在多节段CSM患者中的临床和生物力学结果的证据。对2013年至2018年在拉什大学接受混合前路减压与重建的连续患者进行了一项回顾性研究。分析术前临床和影像学变量,以确定导致手术入路决策的具体因素。此外,我们进行了一项系统评价和荟萃分析,以评估在手术时间、失血量、颈椎前凸、患者报告结局(PRO)、融合率和并发症方面的优势。混合手术(HS)用于存在多节段CSM并伴有椎体后方狭窄或急性后凸畸形的病例。我们的荟萃分析强调,3节段颈椎前路椎间盘切除融合术(ACDF)与混合技术在PRO、并发症和成功融合率方面具有可比性。此外,与2节段椎体次全切除术相比,混合融合术可增加术后颈椎前凸、提高融合率、降低总并发症率、降低植入物失败/网片下沉率并减少失血量。结合颈椎椎体次全切除术和椎间盘切除术的颈椎混合技术是一种平衡的选择,具有两种常用颈椎手术在多节段CSM患者中的优点。关于混合技术的文献表明,在多节段ACDF不可行的情况下,联合椎间盘切除术和椎体次全切除术优于2节段椎体次全切除术,并发症发生率更低,临床结局改善,脊柱对线矫正,生物力学性能更强。