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附着于精子的IgG抗精子抗体与输精管吻合术后的不育症无关。

IgG antisperm antibodies attached to sperm do not correlate with infertility following vasovasostomy.

作者信息

Newton R A

机构信息

Division of Urology, Newton-Wellesley Hospital, MA 02162.

出版信息

Microsurgery. 1988;9(4):278-80. doi: 10.1002/micr.1920090413.

DOI:10.1002/micr.1920090413
PMID:3231077
Abstract

The sperm of 12 men postvasovasostomy was tested for antisperm antibodies by means of a mixed antiglobulin reaction (MAR) test. Agglutinating antibodies were found in 58% of these patients: 50% of the men whose partners became pregnant and 75% of those whose partners did not become pregnant. No significant difference in the level of antibody attachment could be found between the fertile group and the infertile group. Damage to the testis and epididymis following vasectomy seems more likely to interfere with subsequent fertility following vasectomy reversal.

摘要

通过混合抗球蛋白反应(MAR)试验对12名输精管复通术后男性的精子进行抗精子抗体检测。在这些患者中,58%发现有凝集抗体:伴侣怀孕的男性中有50%,伴侣未怀孕的男性中有75%。在可育组和不育组之间,未发现抗体附着水平有显著差异。输精管结扎术后睾丸和附睾的损伤似乎更有可能干扰输精管复通术后的后续生育能力。

相似文献

1
IgG antisperm antibodies attached to sperm do not correlate with infertility following vasovasostomy.附着于精子的IgG抗精子抗体与输精管吻合术后的不育症无关。
Microsurgery. 1988;9(4):278-80. doi: 10.1002/micr.1920090413.
2
The clinical relevance of classes of immunoglobulins on spermatozoa from infertile and vasovasostomized males.不育男性和输精管吻合术后男性精子上免疫球蛋白类别的临床相关性。
Fertil Steril. 1985 Apr;43(4):621-7. doi: 10.1016/s0015-0282(16)48507-9.
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Low fertility rate in vasovasostomized males and its possible immunologic mechanism.输精管吻合术后男性的低生育率及其可能的免疫机制。
Int J Fertil. 1975;20(3):183-91.
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Identification of antisperm antibodies on sperm of infertile men.不育男性精子上抗精子抗体的鉴定。
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Partial obstruction, not antisperm antibodies, causing infertility after vasovasostomy.
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Correlation of circulating antisperm antibodies to functional success in vasovasostomy.循环抗精子抗体与输精管吻合术功能成功的相关性。
J Urol. 1977 Feb;117(2):189-91. doi: 10.1016/s0022-5347(17)58393-7.
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Epididymal more than testicular abnormalities are associated with the occurrence of antisperm antibodies as evaluated by the MAR test.附睾异常多于睾丸异常与 MAR 试验评估的抗精子抗体的发生有关。
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Temporal recognition of sperm autoantigens by IgM and IgG autoantibodies after vasectomy and vasovasostomy.输精管结扎术和输精管吻合术后IgM和IgG自身抗体对精子自身抗原的时间识别。
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Antisperm antibodies in split ejaculates.分段射精中的抗精子抗体。
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Effect of obesity on sex hormone levels, antisperm antibodies, and fertility after vasectomy reversal.肥胖对输精管复通术后性激素水平、抗精子抗体和生育能力的影响。
Urology. 2010 Oct;76(4):851-6. doi: 10.1016/j.urology.2010.01.055.

引用本文的文献

1
Potential causes and associated conditions with anti-sperm antibody production among infertile males: a systematic literature review.不育男性中抗精子抗体产生的潜在原因及相关情况:一项系统文献综述
BMC Immunol. 2025 Aug 6;26(1):58. doi: 10.1186/s12865-025-00740-5.
2
Role of Antisperm Antibodies in Infertility, Pregnancy, and Potential forContraceptive and Antifertility Vaccine Designs: Research Progress and Pioneering Vision.抗精子抗体在不孕、妊娠以及避孕和抗生育疫苗设计潜力中的作用:研究进展与开拓性展望
Vaccines (Basel). 2019 Sep 16;7(3):116. doi: 10.3390/vaccines7030116.
3
Predictors of success in microsurgical correction of vasal and epididymal obstruction.
输精管和附睾梗阻显微外科矫正成功的预测因素。
Curr Urol Rep. 2001 Dec;2(6):443-7. doi: 10.1007/s11934-001-0037-5.