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循环抗精子抗体与输精管吻合术功能成功的相关性。

Correlation of circulating antisperm antibodies to functional success in vasovasostomy.

作者信息

Sullivan M J, Howe G E

出版信息

J Urol. 1977 Feb;117(2):189-91. doi: 10.1016/s0022-5347(17)58393-7.

DOI:10.1016/s0022-5347(17)58393-7
PMID:833964
Abstract

The serum of 45 men with sperm in the ejaculate post-vasovasostomy was tested for antisperm antibodies. Agglutinating antibodies were found in 48 per cent of the men whose partners became pregnant and in 94 per cent of those whose partners did not become pregnant (p less than 0.01). No such correlation was found for sperm immobilizing antibodies. Spontaneous in vivo autoagglutination was not demonstrated in any of the patients. Although functional failure seems likely to be associated with an immunologic event neither sperm agglutination nor sperm immobilization seems to be the mechanism of that event.

摘要

对45例输精管吻合术后射精中有精子的男性血清进行抗精子抗体检测。在其伴侣怀孕的男性中,48%发现有凝集抗体;在其伴侣未怀孕的男性中,94%发现有凝集抗体(P<0.01)。对于精子制动抗体,未发现此类相关性。在任何患者中均未证实有体内自发凝集现象。虽然功能障碍似乎可能与免疫事件有关,但精子凝集和精子制动似乎都不是该事件的机制。

相似文献

1
Correlation of circulating antisperm antibodies to functional success in vasovasostomy.循环抗精子抗体与输精管吻合术功能成功的相关性。
J Urol. 1977 Feb;117(2):189-91. doi: 10.1016/s0022-5347(17)58393-7.
2
Low fertility rate in vasovasostomized males and its possible immunologic mechanism.输精管吻合术后男性的低生育率及其可能的免疫机制。
Int J Fertil. 1975;20(3):183-91.
3
IgG antisperm antibodies attached to sperm do not correlate with infertility following vasovasostomy.附着于精子的IgG抗精子抗体与输精管吻合术后的不育症无关。
Microsurgery. 1988;9(4):278-80. doi: 10.1002/micr.1920090413.
4
Detection of antisperm antibodies: a cytotoxicity immobilization test.抗精子抗体的检测:细胞毒性固定试验。
Int J Fertil. 1986 Jul-Aug;31(3):207-12.
5
Vasectomy and vasovasostomy in rhesus monkeys: the effect of circulating antisperm antibodies on fertility.恒河猴的输精管切除术和输精管吻合术:循环抗精子抗体对生育能力的影响。
Fertil Steril. 1977 May;28(5):562-9.
6
Association between failure to impregnate after vasovasostomy and sperm agglutinins in semen.输精管吻合术后未能受孕与精液中精子凝集素之间的关联。
Lancet. 1981 Jan 17;1(8212):117-9. doi: 10.1016/s0140-6736(81)90708-x.
7
Immunologic considerations before and after vasovasostomy.输精管吻合术前后的免疫学考量
Fertil Steril. 1983 Oct;40(4):497-9. doi: 10.1016/s0015-0282(16)47362-0.
8
Partial obstruction, not antisperm antibodies, causing infertility after vasovasostomy.
J Urol. 1998 Mar;159(3):827-30.
9
The clinical significance of antisperm antibodies in male subfertility.
Br J Urol. 1977;49(7):757-62. doi: 10.1111/j.1464-410x.1977.tb04567.x.
10
Immunological status of patients before and after vasovasostomy as determined by the immunobead antisperm antibody test.通过免疫珠抗精子抗体试验测定输精管吻合术前和术后患者的免疫状态。
J Urol. 1989 Sep;142(3):752-5. doi: 10.1016/s0022-5347(17)38877-8.

引用本文的文献

1
Complications of vasectomy.输精管结扎术的并发症。
Can Fam Physician. 1983 Jul;29:1335-7.
2
Testicular obstruction: clinicopathological studies.睾丸梗阻:临床病理研究
Ann R Coll Surg Engl. 1990 Nov;72(6):396-407.