Li Juanhong, Li Tianzuo, Li Guiying, Liu Hongfu, Zhang Xiaogai
Department of Pain Medicine, Beijing Shijitan Hospital, Capital Medical University.
Department of Nuclear Medicine, Beijing Geriatric Hospital, Beijing, China.
Medicine (Baltimore). 2020 Apr;99(16):e19819. doi: 10.1097/MD.0000000000019819.
Phantom limb pain (PLP) refers to a common complication following amputation, which is characterized by intractable pain in the absent limb, phantom limb sensation, and stump pain. The definitive pathogenesis of PLP has not been fully understood, and the treatment of PLP is still a great challenge. Till now, ozone injection has never been reported for the treatment of PLP.
We report 3 cases: a 68-year-old man, a 48-year-old woman, and a 46-year-old man. All of them had an amputation history and presented with stump pain, phantom limb sensation, and sharp pain in the phantom limb. Oral analgesics and local blocking in stump provided no benefits.
They were diagnosed with PLP.
We performed selective nerve root ozone injection combined with ozone injection in the stump tenderness points.
There were no adverse effects. Postoperative, PLP, and stump pain were significantly improved. During the follow-up period, the pain was well controlled.
Selective nerve root injection of ozone is safe and the outcomes were favorable. Ozone injection may be a new promising approach for treating PLP.
幻肢痛（PLP）是截肢术后常见的并发症，其特征为缺失肢体出现顽固性疼痛、幻肢感觉和残端痛。PLP的确切发病机制尚未完全明确，其治疗仍是一项巨大挑战。迄今为止，尚未有臭氧注射治疗PLP的报道。
我们报告3例病例：一名68岁男性、一名48岁女性和一名46岁男性。他们均有截肢史，表现为残端痛、幻肢感觉和幻肢锐痛。口服镇痛药和残端局部封闭治疗均无效。
他们被诊断为PLP。
我们进行了选择性神经根臭氧注射，并在残端压痛点注射臭氧。
未出现不良反应。术后，PLP和残端痛明显改善。随访期间，疼痛得到良好控制。
选择性神经根臭氧注射安全且效果良好。臭氧注射可能是治疗PLP的一种新的有前景的方法。
