Department of Gastroenterology and Hepatology, University of California San Francisco, Fresno, CA 93721, USA.
Department of Internal Medicine, Texas Tech University, Paul L Foster School of Medicine, El Paso, TX 79905, USA.
Dis Mon. 2020 Nov;66(11):100986. doi: 10.1016/j.disamonth.2020.100986. Epub 2020 Apr 17.
Pancreatic fluid collections (PFC), including pancreatic pseudocysts and walled-off pancreatic necrosis, are a known complication of severe acute pancreatitis. A majority of the PFCs remain asymptomatic and resolve spontaneously. However, some PFCs persist and can become symptomatic. Persistent PFCs can also cause further complications such as the gastric outlet, intestinal, or biliary obstruction and infection. Surgical interventions are indicated for the drainage of symptomatic sterile and infected PFCs. Management of PFCs has evolved from a primarily surgical or percutaneous approach to a less invasive endoscopic approach. Endoscopic interventions are associated with improved outcomes with lesser chances of complications, faster recovery time, and lower healthcare utilization. Endoscopic ultrasound-guided drainage of PFCs using lumen-apposing metal stents has become the preferred approach for the management of symptomatic and complicated PFCs.
胰腺液体积聚（PFC），包括胰腺假性囊肿和胰腺脓肿，是重症急性胰腺炎的一种已知并发症。大多数 PFC 无症状且会自发消退。然而，一些 PFC 持续存在并可能出现症状。持续性 PFC 还可能导致其他并发症，如胃出口、肠道或胆道梗阻和感染。对于有症状的无菌性和感染性 PFC，手术干预是指征。PFC 的治疗已经从主要的手术或经皮方法演变为创伤更小的内镜方法。内镜干预与改善结果相关，并发症的机会更少，恢复时间更快，医疗保健利用率更低。内镜超声引导下使用 lumen-apposing 金属支架引流 PFC 已成为治疗有症状和复杂 PFC 的首选方法。
