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[诱发电位在神经外科重症监护病房中的价值]

[The value of evoked potentials in the neurosurgical intensive care unit].

作者信息

Nau H E, Wiedemayer H, Dalbah A, Engel W, Mais J

机构信息

Neurochirurgische Universitätsklinik Essen.

出版信息

Neurochirurgia (Stuttg). 1988 Sep;31 Suppl 1:170-4. doi: 10.1055/s-2008-1053929.

Abstract

In the neurosurgical intensive care unit 135 patients were studied by means of multi-modality evoked potentials. The majority part of them had low scores on the Glasgow Coma Scale and a higher lever of coma according to WFNS. This fact explains the high mortality (52 per cent). These patient data were compared with the changes of evoked responses (ER) in order to learn something about the value of ER in localisation of lesions, staging, and predicting the outcome of the patients. A classification of EP alterations is introduced. There was no correlation between alteration of evoked potentials and coma stage. The analysis of latencies and inter-peak latencies revealed no correlation between comatous and alert patients. Cerebral conduction time (CCT) did not give further information. In cases of brainstem lesions the alteration of evoked responses were more marked than in the other patients. Most of the patients died who had initially marked changes in ER. The sensitivity of BAER was greater than of SSEP. A loss of response was more frequent in BAER. In deep coma stages the motor evoked responses disappeared. This fact induces problems in diagnosing brain death. Evoked potentials yield further information in patients with coma and drug therapy. They are useful in follow-ups, esp. in predicting the outcome. Evoked responses complete clinical and findings obtained via the diagnostic equipment.

摘要

在神经外科重症监护病房,对135例患者进行了多模态诱发电位研究。他们中的大多数人格拉斯哥昏迷量表评分较低,根据世界神经外科联合会(WFNS)标准昏迷程度较高。这一事实解释了高死亡率(52%)。将这些患者数据与诱发电反应(ER)的变化进行比较,以便了解ER在病变定位、分期和预测患者预后方面的价值。引入了诱发电位改变的分类。诱发电位改变与昏迷阶段之间没有相关性。对潜伏期和峰间潜伏期的分析显示,昏迷患者和清醒患者之间没有相关性。脑传导时间(CCT)没有提供更多信息。在脑干病变的病例中,诱发电反应的改变比其他患者更明显。最初ER有明显变化的大多数患者死亡。脑干听觉诱发电位(BAER)的敏感性高于体感诱发电位(SSEP)。BAER中反应消失更为常见。在深度昏迷阶段,运动诱发电反应消失。这一事实在诊断脑死亡时引发了问题。诱发电位在昏迷和药物治疗患者中提供了更多信息。它们在随访中很有用,尤其是在预测预后方面。诱发电反应完善了通过诊断设备获得的临床和检查结果。

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