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使用正电子发射断层显像/计算机断层扫描(PET/CT)辅助孤立性肺结节病例的临床决策:一种概率方法。

Use of PET/CT to aid clinical decision-making in cases of solitary pulmonary nodule: a probabilistic approach.

作者信息

Mourato Felipe Alves, Brito Ana Emília Teixeira, Romão Monique Sampaio Cruz, Santos Renata Guerra Galvão, de Almeida Cristiana Altino, de Almeida Filho Paulo José, Leal Aline Lopes Garcia

机构信息

Real Hospital Português de Beneficência em Pernambuco, Recife, PE, Brazil.

出版信息

Radiol Bras. 2020 Jan-Feb;53(1):1-6. doi: 10.1590/0100-3984.2019.0034.

DOI:10.1590/0100-3984.2019.0034
PMID:32313329
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7159041/
Abstract

OBJECTIVE

To determine the frequency with which F-FDG-PET/CT findings change the probability of malignancy classification of solitary pulmonary nodules.

MATERIALS AND METHODS

This was a retrospective analysis of all F-FDG-PET/CT examinations performed for the investigation of a solitary pulmonary nodule between May 2016 and May 2017. We reviewed medical records and PET/CT images to collect the data necessary to calculate the pre-test probability of malignancy using the Swensen model and the Herder model. The probability of malignancy was classified as low if < 5%, intermediate if 5-65%, and high if > 65%. Cases classified as intermediate in the Swensen model were reclassified by the Herder model.

RESULTS

We reviewed the records for 33 patients, of whom 17 (51.5%) were male. The mean age was 68.63 ± 12.20 years. According to the Swensen model, the probability of malignancy was intermediate in 23 cases (69.7%). Among those, the application of the Herder model resulted in the probability of malignancy being reclassified as low in 6 (26.1%) and as high in 8 (34.8%).

CONCLUSION

F-FDG-PET/CT was able to modify the probability of malignancy classification of a solitary pulmonary nodule in more than 50% of the cases evaluated.

摘要

目的

确定F-FDG-PET/CT检查结果改变孤立性肺结节恶性分类概率的频率。

材料与方法

这是一项对2016年5月至2017年5月期间为调查孤立性肺结节而进行的所有F-FDG-PET/CT检查的回顾性分析。我们查阅了病历和PET/CT图像,以收集使用斯文森模型和赫德模型计算恶性肿瘤预测试概率所需的数据。如果恶性概率<5%,则分类为低;如果为5%-65%,则分类为中;如果>65%,则分类为高。在斯文森模型中分类为中等的病例,由赫德模型重新分类。

结果

我们回顾了33例患者的记录,其中17例(51.5%)为男性。平均年龄为68.63±12.20岁。根据斯文森模型,23例(69.7%)的恶性概率为中等。其中,应用赫德模型后,6例(26.1%)的恶性概率重新分类为低,8例(34.8%)重新分类为高。

结论

在超过50%的评估病例中,F-FDG-PET/CT能够改变孤立性肺结节的恶性分类概率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c145/7159041/6f09d52ad66b/rb-53-01-0001-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c145/7159041/c1381c0da52f/rb-53-01-0001-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c145/7159041/6f09d52ad66b/rb-53-01-0001-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c145/7159041/c1381c0da52f/rb-53-01-0001-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c145/7159041/6f09d52ad66b/rb-53-01-0001-g02.jpg

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