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Heat-labile enterotoxin produced by Escherichia coli serogroup O149 isolated from diarrheic calves.从腹泻犊牛中分离出的大肠杆菌O149血清群产生的热不稳定肠毒素。
Infect Immun. 1977 Mar;15(3):1002-3. doi: 10.1128/iai.15.3.1002-1003.1977.
2
Detection of virulence factors of Escherichia coli focused on prevalence of EAST1 toxin in stool of diarrheic and non-diarrheic piglets and presence of adhesion involving virulence factors in astA positive strains.检测大肠杆菌的毒力因子，重点关注腹泻和非腹泻仔猪粪便中 EAST1 毒素的流行情况，以及粘附相关毒力因子在 astA 阳性菌株中的存在情况。
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3
Prevalence of the enteroaggregative Escherichia coli heat-stable enterotoxin 1 gene and its relationship with fimbrial and enterotoxin genes in E. coli isolated from diarrheic piglets.从腹泻仔猪分离的大肠杆菌中肠聚集性大肠杆菌热稳定肠毒素1基因的流行情况及其与菌毛和肠毒素基因的关系
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Etiologic diagnosis of diarrheal disease of calves: frequency and methods for detecting enterotoxin and K99 antigen production by Escherichia cola.犊牛腹泻病的病因诊断：大肠杆菌产生肠毒素和K99抗原的检测频率及方法
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Differences in bindings to the GM1 receptor by heat-labile enterotoxin of human and porcine Escherichia coli strains.人源和猪源大肠杆菌菌株的不耐热肠毒素与GM1受体结合的差异。
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Escherichia coli enterotoxin: purification, partial characterization, and immunological observations.大肠杆菌肠毒素：纯化、部分特性鉴定及免疫学观察
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Heat-stable Escherichia coli enterotoxin production in vivo.体内热稳定型大肠杆菌肠毒素的产生
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An outbreak of gastroenteritis due to a heat-labile enterotoxin-producing strain of Escherichia coli.一起由产热不稳定肠毒素的大肠杆菌菌株引起的肠胃炎暴发。
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Enterotoxigenic Escherichia coli strains belonging to a new serogroup, Escherichia coli O166.属于一个新血清群的产肠毒素大肠杆菌菌株，即大肠杆菌O166。
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引用本文的文献

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Foodborne enterotoxigenic Escherichia coli: detection and enumeration by DNA colony hybridization.食源性产肠毒素大肠杆菌：通过DNA菌落杂交进行检测和计数
Appl Environ Microbiol. 1983 Apr;45(4):1324-30. doi: 10.1128/aem.45.4.1324-1330.1983.
2
Purification and chemical characterization of the heat-stable enterotoxin produced by porcine strains of enterotoxigenic Escherichia coli.产肠毒素大肠杆菌猪菌株产生的热稳定肠毒素的纯化及化学特性分析
Infect Immun. 1978 Mar;19(3):1021-30. doi: 10.1128/iai.19.3.1021-1030.1978.

本文引用的文献

1
The effect of cell-free fluids prepared from cultures of human and animal enteropathogenic strains of Escherichia coli on ligated intestinal segments of rabbits and pigs.从人和动物肠道致病性大肠杆菌培养物中制备的无细胞液对兔和猪结扎肠段的影响。
J Med Microbiol. 1970 Aug;3(3):403-9. doi: 10.1099/00222615-3-3-403.
2
The relationship between two apparently different enterotoxins produced by enteropathogenic strains of Escherichia coli of porcine origin.猪源致病性大肠杆菌产生的两种明显不同的肠毒素之间的关系。
J Med Microbiol. 1970 Aug;3(3):387-401. doi: 10.1099/00222615-3-3-387.
3
Use of suckling mice for detection of enteropathogenicity of Escherichia coli isolated from calves and pigs.利用乳鼠检测从犊牛和猪分离出的大肠杆菌的肠致病性。
Proc Annu Meet U S Anim Health Assoc. 1973(77):644-9.
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Tissue-culture assay of antibodies to heat-labile Escherichia coli enterotoxins.对不耐热大肠杆菌肠毒素抗体的组织培养测定
N Engl J Med. 1974 Jul 18;291(3):117-21. doi: 10.1056/NEJM197407182910302.
5
Detection of heat-labile Escherichia coli enterotoxin with the use of adrenal cells in tissue culture.利用组织培养中的肾上腺细胞检测不耐热大肠杆菌肠毒素。
Science. 1974 Jan 25;183(4122):334-6. doi: 10.1126/science.183.4122.334.
6
Further observations on Escherichia coli enterotoxins with particular regard to those produced by atypical piglet strains and by calf and lamb strains: the transmissible nature of these enterotoxins and of a K antigen possessed by calf and lamb strains.关于大肠杆菌肠毒素的进一步观察，特别是关于非典型仔猪菌株以及犊牛和羔羊菌株所产生的肠毒素：这些肠毒素以及犊牛和羔羊菌株所具有的一种K抗原的可传播性质。
J Med Microbiol. 1972 May;5(2):243-50. doi: 10.1099/00222615-5-2-243.
7
Test for Escherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu.利用幼鼠检测大肠杆菌肠毒素：在檀香山儿童腹泻研究中的应用
J Infect Dis. 1972 Apr;125(4):407-11. doi: 10.1093/infdis/125.4.407.
8
The prevalence of enterotoxigenic Escherichia coli in the feces of calves with diarrhea.腹泻犊牛粪便中产肠毒素大肠杆菌的流行情况。
Can J Comp Med. 1976 Jul;40(3):241-6.

从腹泻犊牛中分离出的大肠杆菌O149血清群产生的热不稳定肠毒素。

Heat-labile enterotoxin produced by Escherichia coli serogroup O149 isolated from diarrheic calves.

作者信息

Ellis R P, Kienholz J C

出版信息

Infect Immun. 1977 Mar;15(3):1002-3. doi: 10.1128/iai.15.3.1002-1003.1977.

DOI:10.1128/iai.15.3.1002-1003.1977
PMID:323141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC421474/
Abstract

Nine strains of Escherichia coli serogroup O149 isolated from diarrheic calves were found to produce a heat-labile enterotoxin. The heat-labile enterotoxin activity was destroyed by heat (85 degrees C/30 min) and was neutralized by rabbit anti-heat-labile enterotoxin. One of the strains also produced a heat-stable enterotoxin.

摘要

从腹泻犊牛中分离出的9株大肠杆菌O149血清型菌株被发现能产生一种不耐热肠毒素。不耐热肠毒素活性经加热（85℃/30分钟）后被破坏，并能被兔抗不耐热肠毒素中和。其中一株菌株还产生了一种耐热肠毒素。