Health Sciences Department, Université du Québec à Chicoutimi, Québec, Canada.
Groupe de recherche interdisciplinaire sur les maladies neuromusculaires (GRIMN), Centre intégré universitaire de santé et de services sociaux du Saguenay-Lac-St-Jean, Hôpital de Jonquière, Québec, Canada.
Muscle Nerve. 2020 Jul;62(1):95-102. doi: 10.1002/mus.26893. Epub 2020 May 3.
Myotonic dystrophy type 1 (DM1) is a multisystemic neuromuscular disease that causes balance problems. The objective of this study was to assess the construct validity of the Mini-BESTest among adults with DM1.
Fifty-nine individuals with late-onset or adult phenotypes of DM1 were recruited. Participants performed the Mini-BESTest, 10-Meter Walk Test (10mWT), 6-Minute Walk Test (6MWT), and Timed Up & Go (TUG) and were questioned on their tendency to lose balance and whether they fell in the past month.
Scores on the Mini-BESTest were significantly different between phenotypes and CTG repeat numbers (P < .02). Significant correlations were found with the 10mWT, 6MWT, and the TUG (r = 0.77-0.84; P < .001). A cutoff score of 21.5 was found to identify fallers with 90% posttest accuracy.
The Mini-BESTest demonstrates evidence of construct validity when assessing balance in the DM1 population.
肌强直性营养不良 1 型（DM1）是一种多系统神经肌肉疾病，可导致平衡问题。本研究的目的是评估 Mini-BESTest 在 DM1 成人中的构念效度。
招募了 59 名迟发性或成年表型 DM1 患者。参与者进行 Mini-BESTest、10 米步行测试（10mWT）、6 分钟步行测试（6MWT）和计时起立行走测试（TUG），并询问他们失去平衡的倾向以及他们在过去一个月是否摔倒过。
Mini-BESTest 的评分在表型和 CTG 重复数之间存在显著差异（P <.02）。与 10mWT、6MWT 和 TUG 呈显著相关（r = 0.77-0.84；P <.001）。发现 21.5 的截断值可识别出 90%的后验准确率的跌倒者。
Mini-BESTest 在评估 DM1 人群的平衡时具有构念效度的证据。
