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[下颌骨朗格汉斯细胞组织细胞增多症:一例报告]

[Mandibular Langerhans cell histiocytosis: a case report].

作者信息

Wu Jia-Shun, Zhang Wei-Long, Li Zhu-Feng, Wang Hao-Fan, Yang Xiao, Zhang Mei, Yang Ming-Zhong, Chen Yu, Tang Ya-Ling

机构信息

State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

出版信息

Hua Xi Kou Qiang Yi Xue Za Zhi. 2020 Apr 1;38(2):224-227. doi: 10.7518/hxkq.2020.02.019.

DOI:10.7518/hxkq.2020.02.019
PMID:32314899
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7184281/
Abstract

Langerhans cell histiocytosis is commonly found in cranial bones and rarely found in the mandible. This article presents a case of mandibular Langerhans cell histiocytosis and discusses its pathogeny, clinical features, diagnosis, and treatment.

摘要

朗格汉斯细胞组织细胞增多症常见于颅骨,而在下颌骨中罕见。本文报告一例下颌骨朗格汉斯细胞组织细胞增多症病例,并对其病因、临床特征、诊断及治疗进行讨论。

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The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.2016 年版世界卫生组织髓系肿瘤和急性白血病分类。
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Potential clinical implications of BRAF mutations in histiocytic proliferations.BRAF突变在组织细胞增殖中的潜在临床意义。
Oncotarget. 2014 Jun 30;5(12):4060-70. doi: 10.18632/oncotarget.2061.
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Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation.携带 BRAF V600E 突变的多系统和难治性 Erdheim-Chester 病和朗格汉斯细胞组织细胞增生症中维莫非尼的显著疗效。
Blood. 2013 Feb 28;121(9):1495-500. doi: 10.1182/blood-2012-07-446286. Epub 2012 Dec 20.
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Cell-specific gene expression in Langerhans cell histiocytosis lesions reveals a distinct profile compared with epidermal Langerhans cells.朗格汉斯细胞组织细胞增生症病变中的细胞特异性基因表达与表皮朗格汉斯细胞相比呈现出独特的特征。
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Langerin (CD207) staining in normal pediatric tissues, reactive lymph nodes, and childhood histiocytic disorders.正常儿科组织、反应性淋巴结及儿童组织细胞疾病中的朗格汉斯蛋白(CD207)染色
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Nature. 2002 Jun 27;417(6892):949-54. doi: 10.1038/nature00766. Epub 2002 Jun 9.
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Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules.朗格素,一种对朗格汉斯细胞具有特异性的新型C型凝集素,是一种诱导伯贝克颗粒形成的内吞受体。
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