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下颌骨朗格汉斯细胞组织细胞增多症:两例报告及文献复习

Langerhans cell histiocytosis of the mandible: two case reports and literature review.

作者信息

Hwang Dae-Seok, Lee Jun Sang, Kim Uk-Kyu, Park Hae Ryoun, Ryu Mi Heon, Lee Ji Hye, Jung Yun-Hoa, Kim Gyoo Cheon

机构信息

Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University, Yangsan, Korea.

Department of Translational Dental Science, School of Dentistry, Pusan National University, Yangsan, Korea.

出版信息

J Korean Assoc Oral Maxillofac Surg. 2019 Jun;45(3):167-172. doi: 10.5125/jkaoms.2019.45.3.167. Epub 2019 Jun 28.

DOI:10.5125/jkaoms.2019.45.3.167
PMID:31334105
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6620304/
Abstract

Langerhans cell histiocytosis (LCH) is a rare disorder characterized by the proliferation of dendritic cells resulting in local or systemic symptoms. The clinical symptoms of patients with Langerhans cell histiocytosis depend on the site and the degree of involvement. This article describes two case histories of unifocal bony Langerhans cell histiocytosis with mandibular involvement and further discusses the appropriate management of such via a review of the literature.

摘要

朗格汉斯细胞组织细胞增多症(LCH)是一种罕见的疾病,其特征为树突状细胞增殖,可导致局部或全身症状。朗格汉斯细胞组织细胞增多症患者的临床症状取决于受累部位和程度。本文描述了两例累及下颌骨的单灶性骨朗格汉斯细胞组织细胞增多症的病例,并通过文献综述进一步讨论了对此类疾病的恰当治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/088c/6620304/1897ac0eb40a/jkaoms-45-167-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/088c/6620304/5df45f43e384/jkaoms-45-167-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/088c/6620304/c80175f9cb27/jkaoms-45-167-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/088c/6620304/38b54cef2c7a/jkaoms-45-167-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/088c/6620304/cdb675ff2a21/jkaoms-45-167-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/088c/6620304/7e7212d02664/jkaoms-45-167-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/088c/6620304/1897ac0eb40a/jkaoms-45-167-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/088c/6620304/5df45f43e384/jkaoms-45-167-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/088c/6620304/c80175f9cb27/jkaoms-45-167-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/088c/6620304/38b54cef2c7a/jkaoms-45-167-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/088c/6620304/cdb675ff2a21/jkaoms-45-167-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/088c/6620304/7e7212d02664/jkaoms-45-167-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/088c/6620304/1897ac0eb40a/jkaoms-45-167-g006.jpg

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本文引用的文献

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Clinical features and treatment outcomes of Langerhans cell histiocytosis: a nationwide survey from Korea histiocytosis working party.朗格汉斯细胞组织细胞增多症的临床特征与治疗结果:韩国组织细胞增多症工作组的全国性调查
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Langerhans cell histiocytosis (LCH): guidelines for diagnosis, clinical work-up, and treatment for patients till the age of 18 years.
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Int J Surg Case Rep. 2023 Nov;112:108940. doi: 10.1016/j.ijscr.2023.108940. Epub 2023 Oct 11.
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