Department of Surgery, Mayo Clinic, 200 1st ST SW, Rochester, MN, 55905, USA.
Mayo Clinic Robert D and Patricia E Kern Center for the Science of Health Care Delivery, Rochester, MN, USA.
Obes Surg. 2020 Aug;30(8):2870-2876. doi: 10.1007/s11695-020-04619-9.
Traditional duodenal switch (DS) typically leaves a short common channel and is infrequently performed in part due to increased risk of malnutrition. We compared nutritional deficiencies between DS with a moderate channel length and standard proximal Roux-en-Y gastric bypass (RYGB).
We conducted a retrospective review of 61 matched pairs who underwent DS or RYGB using our institutional database; patients were matched on sex, age, race, and BMI. DS was performed with a common channel length between 120 and 150 cm. Thirty-day complications, total body weight loss (TBWL) %, and nutritional labs up to 24 months were compared using paired t test and Wilcoxon rank sum tests.
Weight loss was similar at each time point (all p > 0.1). DS patients had lower vitamin D levels at 6 months, lower calcium levels at 6 and 12 months, and lower hemoglobin at 12 months and otherwise equivalent (all p < 0.05). Revision was rare (1 DS; 0 RYGB). There were no differences in short-term complications (p = 0.28).
DS with a moderate common channel length is safe with a low revision rate. Weight loss and nutritional outcomes appear to be comparable to RYGB, and it may be considered an effective RYGB alternative.
传统的十二指肠转流术(DS)通常留有较短的共同通道,并且由于营养不良风险增加,其应用并不常见。我们比较了具有中等通道长度的 DS 和标准近端 Roux-en-Y 胃旁路术(RYGB)之间的营养缺乏情况。
我们使用我们的机构数据库对 61 对接受 DS 或 RYGB 的患者进行了回顾性研究;患者在性别、年龄、种族和 BMI 方面进行匹配。DS 的共同通道长度在 120 至 150cm 之间。使用配对 t 检验和 Wilcoxon 秩和检验比较 30 天并发症、总体重减轻(TBWL)%和 24 个月内的营养实验室结果。
在每个时间点体重减轻相似(均 p>0.1)。DS 患者在 6 个月时维生素 D 水平较低,在 6 个月和 12 个月时钙水平较低,在 12 个月时血红蛋白水平较低,但其他方面无差异(均 p<0.05)。修订手术罕见(1 例 DS;0 例 RYGB)。短期并发症无差异(p=0.28)。
具有中等共同通道长度的 DS 是安全的,修订率低。体重减轻和营养结果似乎与 RYGB 相当,并且可以被认为是 RYGB 的有效替代方法。