Mehrad Mitra, Colby Thomas V, Rossi Giulio, Cavazza Alberto
From the Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee (Mehrad).
the Department of Pathology, Mayo Clinic, Scottsdale, Arizona (Colby).
Arch Pathol Lab Med. 2020 Dec 1;144(12):1501-1508. doi: 10.5858/arpa.2020-0007-RA.
CONTEXT.—: Transbronchial cryobiopsy is an emerging procedure to obtain lung tissue for diagnosis of interstitial lung disease and has gained popularity because it is less invasive and has a lower rate of complications compared with nonselective surgical lung biopsy.
OBJECTIVE.—: To provide an overview of the status of the medical literature regarding transbronchial cryobiopsy.
DATA SOURCES.—: A literature search was performed using PubMed search engine. The terms "cryobiopsy" or "cryoprobe" and "interstitial lung disease" or "diffuse parenchymal lung disease" or "pulmonary fibrosis" were used, with the search concluding at the end of November 2019.
CONCLUSIONS.—: While the diagnostic yield of transbronchial cryobiopsy is slightly lower than surgical lung biopsy, a growing amount of literature suggests that with a multidisciplinary approach cryobiopsy provides diagnostic and prognostic information approaching that of surgical lung biopsy with lower morbidity and mortality.
经支气管冷冻活检是一种用于获取肺组织以诊断间质性肺疾病的新兴技术，因其侵入性较小且与非选择性外科肺活检相比并发症发生率较低而受到欢迎。
概述有关经支气管冷冻活检的医学文献现状。
使用PubMed搜索引擎进行文献检索。检索词为“冷冻活检”或“冷冻探头”以及“间质性肺疾病”或“弥漫性实质性肺疾病”或“肺纤维化”，检索截至2019年11月底。
虽然经支气管冷冻活检的诊断率略低于外科肺活检，但越来越多的文献表明，采用多学科方法时，冷冻活检提供的诊断和预后信息接近外科肺活检，且发病率和死亡率较低。
