Fernández-Calderón Fermín, Vidal-Giné Claudio, Rojas-Tejada Antonio J, Lozano-Rojas Óscar M
Department of Clinical and Experimental Psychology, University of Huelva , Huelva, Spain.
Research Center on Natural Resources, Health and the Environment, University of Huelva , Huelva, Spain.
J Psychoactive Drugs. 2020 Sep-Oct;52(4):344-356. doi: 10.1080/02791072.2020.1752959. Epub 2020 Apr 22.
This study identifies patterns of simultaneous polysubstance use (SPU) in partygoers, their associated characteristics, and their differences in terms of acute effects experienced. We used a web-based survey with 1345 partygoers who reported using at least one substance during the past year, collecting information on drug use and drug-related acute effects experienced at the last party attended. Latent class analysis identified three SPU profiles according to the use of nine substances: (67.7%), (11.6%), and (20.7%). These profiles differed in their sociodemographic characteristics and were associated with different odds of experiencing adverse drug-related effects. Compared with participants with a profile of or , those in the group were at higher odds of experiencing memory impairment, tachycardia, and bad mood after drug use. The only differences between the and groups were in terms of hangover and headache experiences, which were less likely in the latter group (who consume less alcohol). Knowledge regarding the acute adverse drug-related effects experienced by partygoers who use multiple drugs can help to develop interventions for reducing drug-related risks in this population.
本研究确定了参加派对者同时使用多种物质（SPU）的模式、其相关特征以及他们在急性效应方面的差异。我们对1345名参加派对者进行了一项基于网络的调查，这些人报告在过去一年中至少使用过一种物质，收集了他们在最近参加的派对上的药物使用情况以及与药物相关的急性效应信息。潜在类别分析根据九种物质的使用情况确定了三种SPU模式：（67.7%）、（11.6%）和（20.7%）。这些模式在社会人口学特征方面存在差异，并且与经历药物相关不良效应的不同几率相关。与具有或模式的参与者相比，组中的参与者在使用药物后出现记忆障碍、心动过速和情绪不佳的几率更高。组和组之间的唯一差异在于宿醉和头痛经历，后一组（饮酒较少）出现这些情况的可能性较小。了解使用多种药物的参加派对者所经历的急性药物相关不良效应，有助于制定干预措施以降低该人群中与药物相关的风险。
