Doherty Emily A, Moyers Susette A, Crockett-Barbera Erica K, Appleseth Hannah, Leffingwell Quinn, Richards Veronica, Chiaf Ashleigh L, Croff Julie M
Department of Rural Health, Oklahoma State University Center for Health Sciences, Tulsa, OK 74107, USA.
Department of Psychology, Oklahoma State University, Stillwater, OK 74074, USA.
Addict Behav. 2025 Oct;169:108394. doi: 10.1016/j.addbeh.2025.108394. Epub 2025 Jun 2.
Substance use is prevalent among adolescents and young adults (AYAs). Polysubstance use is associated with poorer outcomes than single substance use alone. However, few studies have examined patterns of daily use of substance(s) among AYA females, as well as associated factors.
We aimed to 1) identify daily substance use patterns in AYA females, and 2) examine the association with select predisposing factors (i.e. impulsivity and depressive symptoms) and risky sexual behavior.
A sample of 15-24 year old females with recent binge drinking (n = 149), reported daily substance use and sexual activity through weekly Timeline Followback interviews over a 1-month period (n = 4224). Impulsivity, depressive symptoms, and sociodemographics were measured at baseline. Day-level latent class analysis was conducted to characterize patterns of substance use, and Bolck, Croon, and Hagenaars three-step approach was utilized to examine the association of predisposing factors and other health behaviors with latent class membership.
Four day-level classes of substance use were identified: 1) little-to-no-use (54.1 % of days); 2) vaping-only (28.2 % of days); 3) cannabis-only (10.5 % of days); and 4) heavy-alcohol-and-cannabis (some smoking and vaping; 7.2 % of days). More class 4 days were associated with higher impulsivity than class 1 and 3 (M = 0.42 vs. -0.17 and -0.13), more depressive symptoms than class 1 and 2 (M = 0.77 vs. -0.19 and 0.01), and more same day condomless sex than class 1 and 2 (19 % vs. 8 % and 7 %).
AYA females exhibit varied patterns of daily substance use including polysubstance use. Knowledge of risk factors associated with problematic use as well as co-occurring risky sexual behavior can inform targeted intervention and prevention efforts.
物质使用在青少年和青年成年人（AYA）中很普遍。与单一物质使用相比，多种物质使用与更差的结果相关。然而，很少有研究调查AYA女性的日常物质使用模式以及相关因素。
我们旨在1）确定AYA女性的日常物质使用模式，以及2）研究与选定的易患因素（即冲动性和抑郁症状）及危险性行为的关联。
对15至24岁近期有暴饮行为的女性样本（n = 149），通过为期1个月的每周时间线追溯访谈报告日常物质使用和性活动（n = 4224）。在基线时测量冲动性、抑郁症状和社会人口统计学特征。进行日水平潜在类别分析以描述物质使用模式，并采用博尔克、克鲁恩和哈根纳斯三步法研究易患因素和其他健康行为与潜在类别成员资格的关联。
确定了四种日水平的物质使用类别：1）极少至不使用（占天数的54.1%）；2）仅使用电子烟（占天数的28.2%）；3）仅使用大麻（占天数的10.5%）；4）大量饮酒和使用大麻（一些吸烟和吸电子烟；占天数的7.2%）。与第1类和第3类相比，第4类天数与更高的冲动性相关（M = 0.42对 -0.17和 -0.13），与第1类和第2类相比，有更多的抑郁症状（M = 0.77对 -0.19和0.01），并且与第1类和第2类相比，同一天无保护性行为更多（19%对8%和7%）。
AYA女性表现出包括多种物质使用在内的不同日常物质使用模式。了解与问题使用以及同时发生的危险性行为相关的风险因素可为有针对性的干预和预防工作提供信息。
