relA基因对脂质A脂肪酰基部分合成的控制。
relA gene control of the synthesis of lipid A fatty acyl moieties.
作者信息
Spencer A, Muller E, Cronan J E, Gross T A
出版信息
J Bacteriol. 1977 Apr;130(1):114-7. doi: 10.1128/jb.130.1.114-117.1977.
Abstract
The incorporation of [14C]acetate into the fatty acid moieties of lipid A was measured during amino acid starvation of rel+ and relA strains of Escherichia coli K-12. The synthesis of the beta-hydroxymyristate and other fatty acid moieties was inhibited two- to fourfold in rel+ strains, whereas no inhibition was observed in relA strains. The fatty acid compositions of the phospholipids synthesized after amino acid starvation or rel+ and relA strains were also determined.
摘要
在大肠杆菌K-12的rel⁺和relA菌株的氨基酸饥饿期间，测定了[¹⁴C]乙酸盐掺入脂质A的脂肪酸部分的情况。rel⁺菌株中β-羟基肉豆蔻酸和其他脂肪酸部分的合成被抑制了两到四倍，而在relA菌株中未观察到抑制作用。还测定了氨基酸饥饿后rel⁺和relA菌株合成的磷脂的脂肪酸组成。
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