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大肠杆菌中脱氧核糖核酸分离的培养基依赖性变异

Medium-dependent variation of deoxyribonucleic acid segregation in Escherichia coli.

作者信息

Cooper S, Weinberger M

出版信息

J Bacteriol. 1977 Apr;130(1):118-27. doi: 10.1128/jb.130.1.118-127.1977.

DOI:10.1128/jb.130.1.118-127.1977
PMID:323220
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC235181/
Abstract

The degree to which deoxyribonucleic acid segregates nonrandomly has been investigated for Escherichia coli B/r growing in different media. The degree of nonrandom segregation observed is dependent on the medium, with segregation becoming less random as the growth rate decreases. This indicates that there must be some varying probabilistic component to the segregation process. A probabilistic modification of the Pierucci-Zuchowski model is proposed as well as a probabilistic model, in which it is proposed that deoxyribonucleic acid strands segregate, with a probability greater than 0.5, in the same direction (toward the same pole) as at the previous cell division.

摘要

对于在不同培养基中生长的大肠杆菌B/r,已对脱氧核糖核酸非随机分离的程度进行了研究。观察到的非随机分离程度取决于培养基,随着生长速率降低,分离变得不那么随机。这表明在分离过程中必定存在某种变化的概率成分。提出了对皮耶鲁奇 - 祖乔夫斯基模型的概率修正以及一个概率模型,在该模型中提出脱氧核糖核酸链以大于0.5的概率沿与前一次细胞分裂相同的方向(朝向同一极)分离。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1887/235181/094e982fa54e/jbacter00305-0132-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1887/235181/094e982fa54e/jbacter00305-0132-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1887/235181/094e982fa54e/jbacter00305-0132-a.jpg

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Non-random segregation of DNA strands in Escherichia coli B-r.大肠杆菌B-r中DNA链的非随机分离
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Probabilistic behavior of DNA segregation in Escherichia coli.大肠杆菌中DNA分离的概率行为。
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