Kilciksiz Can Mişel, Keefe Richard, Benoit James, Öngür Dost, Torous John
Digital Psychiatry Division, Psychosis Research Program, Beth Israel Deaconess Medical Center, Boston, MA, United States of America.
Department of Psychiatry, Harvard Medical School, Boston, MA, United States of America.
Schizophr Res Cogn. 2020 Apr 15;21:100177. doi: 10.1016/j.scog.2020.100177. eCollection 2020 Sep.
Even in the early phases of psychotic spectrum illnesses such as schizophrenia, patients can experience cognitive decline or deficits prior to the onset of psychotic symptoms such as delusions and hallucinations. In this systematic review, we assessed which verbal memory assessments are most widely used in first-episode psychosis and may be applied via digital technologies (smartphone applications, etc.) for use in early detection.
In November 2019, we searched for studies measuring verbal memory in first episode psychosis or schizophrenia over the past 10 years on PubMed and PsycINFO. We screened abstracts of these studies and excluded review studies. Full-texts of included studies were used to identify the verbal memory measurement tests, follow-up frequencies, and sample sizes.
We screened 233 reports and found that 120 original research studies measured verbal memory in first episode psychosis over the past 10 years. Four of these studies specified using a computer, 24 (20%) used a paper-pen format, 1(1%) used both, and 91 (76%) studies did not specify their administration tools or suggest there were offered in digital formats. Thirty-five (30%) studies had follow-up measurements of verbal memory, while 85 (70%) had only a single verbal memory measurement.
While many scales are commonly used to measure verbal memory in first episode psychosis, they are not often administered via digital technology. There is an emerging opportunity to administer these and other tests via digital technologies for expanding access to early detection of cognitive decline in clinical high risk and first-episode psychosis.
即使在精神分裂症等精神病性谱系疾病的早期阶段，患者在妄想和幻觉等精神病性症状出现之前就可能经历认知衰退或缺陷。在本系统评价中，我们评估了哪些言语记忆评估方法在首发精神病中使用最为广泛，并且可以通过数字技术（智能手机应用程序等）应用于早期检测。
2019年11月，我们在PubMed和PsycINFO上搜索了过去10年中测量首发精神病或精神分裂症言语记忆的研究。我们筛选了这些研究的摘要并排除了综述研究。纳入研究的全文用于确定言语记忆测量测试、随访频率和样本量。
我们筛选了233篇报告，发现过去10年中有120项原创研究测量了首发精神病的言语记忆。其中4项研究指定使用计算机，24项（20%）使用纸笔形式，1项（1%）两者都使用，91项（76%）研究未指定其施测工具或表明提供了数字格式。35项（30%）研究对言语记忆进行了随访测量，而85项（70%）仅进行了一次言语记忆测量。
虽然许多量表通常用于测量首发精神病的言语记忆，但它们并不经常通过数字技术进行施测。通过数字技术施测这些及其他测试以扩大对临床高危和首发精神病认知衰退早期检测的可及性，这是一个新出现的机会。
