Department of Ophthalmology, Rigshospitalet-Glostrup, Glostrup, Denmark.
Institute for Clinical Medicine, Aarhus University Faculty of Health Sciences, Aarhus, Denmark.
Acta Ophthalmol. 2020 Nov;98(7):716-725. doi: 10.1111/aos.14449. Epub 2020 Apr 23.
This study evaluates current available endpoints for epiretinal membrane (ERM) surgery and examine their correlation to patient reported outcomes (PRO).
Retrospective study including 38 eyes of 38 patients who underwent cataract extraction and subsequent vitrectomy for idiopathic ERM. The fellow eye was phakic with good visual acuity. The registered outcomes were monocular and binocular visual acuity, stereoacuity, M-chart metamorphopsia score, aniseikonia and aniseikonia tolerance range (ATR). Two questionnaires were completed: the convergence insufficiency symptom survey and Visual Function Questionnaire (VFQ-39).
Median total aniseikonia was 11% (range 0-35). There was a statistically significant correlation between the mean total M-chart score of the study eye and VFQ-Near (Spearman rho: VFQ-Near: -0.54, p < 0.01). There was no correlation between the best corrected visual acuity (BCVA) of the project eye, binocular BCVA, stereoacuity, ATR or mean total aniseikonia and PRO (Spearman p-values > 0.05). There was no correlation between mean total aniseikonia and mean total M-chart score (Spearman rho: 0.21 p = 0.26). There was a large variation between the mean total M-chart scores and questionnaire results.
The mean total M-chart score is currently the best end-points to predict PRO of ERM surgery; however, it is possible to have high M-chart values and have no visual complaints.
本研究评估了用于治疗视网膜内膜(ERM)手术的现有终点,并检查了它们与患者报告的结果(PRO)的相关性。
回顾性研究包括 38 例 38 只眼,这些患者因特发性 ERM 接受白内障摘除术和随后的玻璃体切除术。对侧眼为非晶状体眼,视力良好。登记的结果为单眼和双眼视力、立体视觉、M 图表形觉失真评分、不等像和不等像耐受范围(ATR)。完成了两份问卷:会聚不足症状调查和视觉功能问卷(VFQ-39)。
中位数总不等像为 11%(范围 0-35)。研究眼的平均总 M 图表评分与 VFQ-近视力(Spearman rho:VFQ-近视力:-0.54,p<0.01)之间存在统计学显著相关性。项目眼的最佳矫正视力(BCVA)、双眼 BCVA、立体视觉、ATR 或总平均不等像与 PRO 之间无相关性(Spearman p 值>0.05)。平均总不等像与平均总 M 图表评分之间无相关性(Spearman rho:0.21,p=0.26)。平均总 M 图表评分和问卷结果之间存在很大差异。
目前,平均总 M 图表评分是预测 ERM 手术 PRO 的最佳终点;然而,有可能存在高 M 图表值而没有视觉主诉。