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与骨髓增生异常综合征相关的血栓性血小板减少性紫癜

Thrombotic Thrombocytopenic Purpura Associated with Myelodysplastic Syndrome.

作者信息

Malik Zohra R, Mokraoui Nassim, Razaq Zareen, Severiano Gabriela L, Yanogo Arnaud

机构信息

Internal Medicine, St. John's Episcopal Hospital, Far Rockaway, USA.

Internal Medicine, Ghurki Trust Teaching Hospital, Lahore, PAK.

出版信息

Cureus. 2020 Mar 22;12(3):e7364. doi: 10.7759/cureus.7364.

DOI:10.7759/cureus.7364
PMID:32328376
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7174855/
Abstract

Myelodysplasia and thrombotic thrombocytopenic purpura (TTP) are both rare diseases. TTP is a blood abnormality in which blood clots form in blood vessels leading to fatal outcomes. Myelodysplastic syndrome is a group of disorders caused by poorly formed blood cells or ones that do not work properly. We are hereby presenting the case of a 69-year-old female who presented with anemia, thrombocytopenia, changes in mental status and reduced kidney function, and further investigations revealed that the patient had underlying myelodysplasia.

摘要

骨髓发育异常和血栓性血小板减少性紫癜(TTP)均为罕见疾病。TTP是一种血液异常疾病,血管中会形成血栓,可导致致命后果。骨髓增生异常综合征是一组由血细胞生成不良或功能异常引起的病症。我们在此报告一例69岁女性患者,该患者出现贫血、血小板减少、精神状态改变及肾功能减退,进一步检查发现其患有潜在的骨髓发育异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd9a/7174855/3c1ee998640b/cureus-0012-00000007364-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd9a/7174855/70a26f6b188c/cureus-0012-00000007364-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd9a/7174855/3c1ee998640b/cureus-0012-00000007364-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd9a/7174855/70a26f6b188c/cureus-0012-00000007364-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd9a/7174855/3c1ee998640b/cureus-0012-00000007364-i02.jpg

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TTP and ADAMTS13: When Is Testing Appropriate?血栓性血小板减少性紫癜与ADAMTS13:何时进行检测合适?
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