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血栓性血小板减少性紫癜与皮肌炎相关

Thrombotic Thrombocytopenic Purpura Associated with Dermatomyositis.

作者信息

Malik Zohra R, Shahbaz Amir, Aziz Kashif, Razaq Zareen, Umair Muhammad, Sachmechi Issac

机构信息

Internal Medicine, Icahn School of Medicine at Mount Sinai/Queens Hospital Center, New York City, USA.

Internal Medicine, Icahn School of Medicine at Mount Sinai/Queens Hospital Center, New York, USA.

出版信息

Cureus. 2018 Aug 20;10(8):e3161. doi: 10.7759/cureus.3161.

DOI:10.7759/cureus.3161
PMID:30357036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6197508/
Abstract

Dermatomyositis and thrombotic thrombocytopenic purpura (TTP) are both rare diseases. TTP is a blood abnormality in which blood clots form in blood vessels leading to fatal outcomes. Dermatomyositis is an inflammatory myopathy which causes a distinctive skin rash and muscle weakness. We are hereby presenting the case of a 27-year-old female who presented with characteristic skin findings on the face pathognomic of dermatomyositis and further investigation revealed that she had underlying TTP.

摘要

皮肌炎和血栓性血小板减少性紫癜（TTP）均为罕见疾病。TTP是一种血液异常疾病，血管中会形成血栓，可导致致命后果。皮肌炎是一种炎性肌病，会引发独特的皮疹和肌肉无力。我们在此报告一例27岁女性病例，该患者面部出现了皮肌炎特征性的皮肤表现，进一步检查发现她患有潜在的TTP。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a34a/6197508/07ded009a72d/cureus-0010-00000003161-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a34a/6197508/07ded009a72d/cureus-0010-00000003161-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a34a/6197508/07ded009a72d/cureus-0010-00000003161-i01.jpg

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Juvenile Dermatomyositis (JDM) Complicated by Thrombotic Thrombocytopenic Purpura (TTP) and Purtscher's Retinopathy Responsive to Rituximab: Case Report and Literature Review.青少年皮肌炎（JDM）合并血栓性血小板减少性紫癜（TTP）及对利妥昔单抗有反应的Purtscher视网膜病变：病例报告及文献综述
Front Pediatr. 2020 Aug 4;8:436. doi: 10.3389/fped.2020.00436. eCollection 2020.

本文引用的文献

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Juvenile Dermatomyositis (JDM) Complicated by Thrombotic Thrombocytopenic Purpura (TTP) and Purtscher's Retinopathy Responsive to Rituximab: Case Report and Literature Review.青少年皮肌炎（JDM）合并血栓性血小板减少性紫癜（TTP）及对利妥昔单抗有反应的Purtscher视网膜病变：病例报告及文献综述
Front Pediatr. 2020 Aug 4;8:436. doi: 10.3389/fped.2020.00436. eCollection 2020.
2
Clinical presentation and evaluation of dermatomyositis.皮肌炎的临床表现与评估
Indian J Dermatol. 2012 Sep;57(5):375-81. doi: 10.4103/0019-5154.100486.
3
TTP and ADAMTS13: When Is Testing Appropriate?
血栓性血小板减少性紫癜与ADAMTS13：何时进行检测合适？
Hematology Am Soc Hematol Educ Program. 2007:121-6. doi: 10.1182/asheducation-2007.1.121.
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Hematol Oncol Clin North Am. 2007 Aug;21(4):609-32, v. doi: 10.1016/j.hoc.2007.06.003.
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6
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7
Polymyositis and dermatomyositis.多发性肌炎和皮肌炎。
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Recovery by splenectomy in patients with relapsed thrombotic thrombocytopenic purpura and treatment failure to plasma exchange.
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