Yang Fei, Sun Zheng
Department of Electronic and Communication Engineering, North China Electric Power University, Baoding, Hebei 071003, P.R.China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2020 Apr 25;37(2):358-364. doi: 10.7507/1001-5515.201906061.
Intravascular optical coherence tomography (IVOCT) has emerged as a high-resolution and minimal-invasive imaging technique that provides high-speed visualization of coronary arterial vessel walls and clearly displays the vessel lumen and lesions under the intima. However, morphological gray-scale images cannot provide enough information about the tissue components to accurately characterize the plaque tissues including calcified, fibrous, lipidic and mixed plaques. Quantitative IVOCT ( IVOCT) is necessary to provide the physiological contrast mechanisms and obtain the characteristic parameters of tissues with clinical diagnostic value. In this paper, the progress of IVOCT is reviewed. The current methods for quantitatively measuring optical, elastic and hemodynamic parameters of vessel wall and plaque tissues using IVOCT gray-scale images and raw backscattered signals are introduced and potential development is forecast.
血管内光学相干断层扫描（IVOCT）已成为一种高分辨率、微创成像技术，可对冠状动脉血管壁进行高速可视化，并清晰显示血管腔和内膜下病变。然而，形态学灰度图像无法提供足够的组织成分信息，以准确表征包括钙化、纤维、脂质和混合斑块在内的斑块组织。定量IVOCT（qIVOCT）对于提供生理对比机制并获取具有临床诊断价值的组织特征参数是必要的。本文综述了IVOCT的进展。介绍了目前利用IVOCT灰度图像和原始背向散射信号定量测量血管壁和斑块组织的光学、弹性和血流动力学参数的方法，并对其潜在发展进行了预测。
