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生长抑素类似物在高胰岛素血症短期治疗中的应用

Somatostatin analogue in short term management of hyperinsulinism.

作者信息

Kirk J M, Di Silvio L, Hindmarsh P C, Brook C G

机构信息

Endocrine Unit, Middlesex Hospital, London.

出版信息

Arch Dis Child. 1988 Dec;63(12):1493-4. doi: 10.1136/adc.63.12.1493.

Abstract

Five infants with hypoglycaemia due to hyperinsulinism were treated for between three and 11 days with a somatostatin analogue, which raised the mean blood glucose concentration and lowered the glucose requirements in all. Somatostatin analogue appears to be useful in the short term management of these patients.

摘要

五名因高胰岛素血症导致低血糖的婴儿接受了生长抑素类似物治疗,疗程为三至十一天。治疗后,所有婴儿的平均血糖浓度均有所升高,葡萄糖需求量降低。生长抑素类似物似乎对这些患者的短期治疗有效。

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本文引用的文献

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The effect of somatostatin analogs on secretion of growth, pancreatic, and gastrointestinal hormones in man.
J Clin Endocrinol Metab. 1981 Oct;53(4):675-81. doi: 10.1210/jcem-53-4-675.
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Short-term management of nesidioblastosis using the somatostatin analogue SMS 201-995.
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