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复发性葡萄胎:一例连续发生7次葡萄胎患者的报告。

Recurrent hydatidiform mole: a report of a patient with 7 consecutive moles.

作者信息

Thavarasah A S, Kanagalingam S

机构信息

Department of Obstetrics and Gynaecology, School of Medical Sciences, University Hospital, Bharu, Malaysia.

出版信息

Aust N Z J Obstet Gynaecol. 1988 Aug;28(3):233-5. doi: 10.1111/j.1479-828x.1988.tb01672.x.

Abstract

A rare case of hydatidiform mole occurring 7 consecutive times in a Chinese woman is presented. She was first seen in 1979 at the age of 23 years, with a molar pregnancy and subsequently had 6 consecutive moles, the last being in July, 1986; at this visit the patient and her husband were very depressed, and convinced that a normal pregnancy was unlikely and requested a hysterectomy. They were warned earlier several times, of the possible long-term consequences of a recurrent mole and that their chance of having a normal baby was very remote. A total hysterectomy was performed at her last presentation as the patient requested one, instead of dilatation and curettage for a persistently high HCG and bulky uterus following suction evacuation. Histology revealed an invasive mole. The beta HCG level was less than 4IU/l by the end of September, 1986 and she is still being followed-up.

摘要

本文报道了一名中国女性连续7次发生葡萄胎的罕见病例。她于1979年首次就诊,当时23岁,怀了葡萄胎,随后又连续发生了6次葡萄胎,最后一次是在1986年7月;此次就诊时,患者及其丈夫非常沮丧,坚信不可能有正常妊娠,并要求进行子宫切除术。此前曾多次警告他们,反复发生葡萄胎可能产生的长期后果,以及他们生下正常婴儿的机会非常渺茫。在她最后一次就诊时,由于患者要求,进行了全子宫切除术,而不是在吸宫术后因HCG持续升高和子宫肿大而进行刮宫术。组织学检查显示为侵蚀性葡萄胎。到1986年9月底,β-HCG水平低于4IU/l,她仍在接受随访。

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