Thavarasah A S, Kanagalingam S
Department of Obstetrics and Gynaecology, School of Medical Sciences, University Hospital, Bharu, Malaysia.
Aust N Z J Obstet Gynaecol. 1988 Aug;28(3):233-5. doi: 10.1111/j.1479-828x.1988.tb01672.x.
A rare case of hydatidiform mole occurring 7 consecutive times in a Chinese woman is presented. She was first seen in 1979 at the age of 23 years, with a molar pregnancy and subsequently had 6 consecutive moles, the last being in July, 1986; at this visit the patient and her husband were very depressed, and convinced that a normal pregnancy was unlikely and requested a hysterectomy. They were warned earlier several times, of the possible long-term consequences of a recurrent mole and that their chance of having a normal baby was very remote. A total hysterectomy was performed at her last presentation as the patient requested one, instead of dilatation and curettage for a persistently high HCG and bulky uterus following suction evacuation. Histology revealed an invasive mole. The beta HCG level was less than 4IU/l by the end of September, 1986 and she is still being followed-up.
本文报道了一名中国女性连续7次发生葡萄胎的罕见病例。她于1979年首次就诊，当时23岁，怀了葡萄胎，随后又连续发生了6次葡萄胎，最后一次是在1986年7月；此次就诊时，患者及其丈夫非常沮丧，坚信不可能有正常妊娠，并要求进行子宫切除术。此前曾多次警告他们，反复发生葡萄胎可能产生的长期后果，以及他们生下正常婴儿的机会非常渺茫。在她最后一次就诊时，由于患者要求，进行了全子宫切除术，而不是在吸宫术后因HCG持续升高和子宫肿大而进行刮宫术。组织学检查显示为侵蚀性葡萄胎。到1986年9月底，β-HCG水平低于4IU/l，她仍在接受随访。
