Cohen B A, Schenk V A, Sweeney D B
Department of Neurology, Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee.
Pediatr Neurol. 1988 Jan-Feb;4(1):18-22. doi: 10.1016/0887-8994(88)90019-7.
Sixty-seven children with meningitis, ranging in age from 1 month to 14 years, were studied using brainstem auditory evoked potentials. Abnormal results were present in 60% of the subjects. Serial studies were obtained in 30% of the abnormal patients, 75% of whom demonstrated continued abnormalities on subsequent examination. Abnormal studies were found only in those patients who were 6 years of age or younger. The most prominent finding was an increased interwave interval resulting from increased wave V latencies. Additional abnormalities included an increased slope of the latency-intensity function suggestive of sensory-neural hearing loss. These studies clearly indicate the significance of early detection by the use of evoked potentials in the early diagnosis of hearing disorders in children with meningitis.
对67名年龄在1个月至14岁之间的脑膜炎患儿进行了脑干听觉诱发电位研究。60%的受试者结果异常。30%的异常患者进行了系列研究，其中75%在后续检查中仍显示异常。仅在6岁及以下的患者中发现异常研究。最突出的发现是由于V波潜伏期延长导致的波间期增加。其他异常包括潜伏期-强度函数斜率增加，提示感觉神经性听力损失。这些研究清楚地表明了在脑膜炎患儿听力障碍的早期诊断中，通过诱发电位进行早期检测的重要性。
