Jiang Z D, Liu X Y, Wu Y Y, Zheng M S, Liu H C
Department of Child Health, Children's Hospital, Shanghai Medical University, P.R.C.
Dev Med Child Neurol. 1990 Jun;32(6):473-80. doi: 10.1111/j.1469-8749.1990.tb16972.x.
Sixty children who had recovered from purulent meningitis one to six years earlier were investigated for long-term impairment of brain and auditory function, using brainstem auditory evoked potentials(BAEP) and developmental screening tests. Neurological and/or audiological BAEP abnormalities were found in 23 per cent of the children: 15 per cent had mild brainstem impairment and 12 per cent had hearing dysfunction. Developmental screening tests were administered to 46 children, of whom 61 per cent had normal, 22 per cent questionable and 17 per cent abnormal results. The results of the BAEP significantly correlated with those of the developmental screening tests, suggesting that the neuropsychological development of children with BAEP abnormalities was significantly delayed compared with that of children without BAEP abnormalities. The characteristic finding in a neurologically abnormal BAEP was slightly depressed amplitude of wave V, and the authors suggest that this is the most sensitive BAEP measure for the assessment of brainstem function in children recovered from meningitis.
对60名在1至6年前已从化脓性脑膜炎中康复的儿童进行了调查，采用脑干听觉诱发电位（BAEP）和发育筛查测试来评估其脑功能和听觉功能的长期损害情况。在23%的儿童中发现了神经学和/或听力学BAEP异常：15%有轻度脑干损害，12%有听力功能障碍。对46名儿童进行了发育筛查测试，其中61%结果正常，22%结果存疑，17%结果异常。BAEP的结果与发育筛查测试的结果显著相关，这表明与没有BAEP异常的儿童相比，有BAEP异常的儿童神经心理发育明显延迟。神经学上异常的BAEP的特征性表现是V波幅度略有降低，作者认为这是评估脑膜炎康复儿童脑干功能最敏感的BAEP指标。
