工作场所伤害对阿片类药物依赖、滥用、非法使用和过量用药的影响：36 个月保险索赔回顾性研究。
Impact of workplace injury on opioid dependence, abuse, illicit use and overdose: a 36-month retrospective study of insurance claims.
机构信息
NIOSH, Centers for Disease Control and Prevention, Washignton, District of Columbia, USA
Department of Environmental Health, Boston University School of Public Health, Boston, Massachusetts, USA.
出版信息
Occup Environ Med. 2020 Sep;77(9):648-653. doi: 10.1136/oemed-2020-106535. Epub 2020 Apr 24.
Abstract
OBJECTIVES
To examine the impact of workplace injury on opioid dependence, abuse and overdose (opioid-related morbidity) and if severity of injury increases the hazard of these health effects.
METHODS
We used MarketScan databases to follow injured and propensity score matched non-injured workers, both without prior opioid-related diagnoses. Using a Cox proportional hazard model, we examined the impact of workplace injury on opioid-related morbidity.
RESULTS
The hazard of opioid-related morbidity for injured workers was 1.79 times than that of matched non-injured workers (95% CI 1.89 to 3.60). For medical-only and lost-time injured workers, it was respectively 1.54 (95% CI 1.02 to 2.32) and 2.91 (95% CI 1.75 to 4.84) times that of non-injured workers.
CONCLUSIONS
Reducing workplace injury or severity of workplace injury, as well as efforts to ensure appropriate opioid prescribing for injured workers, may help to reduce the societal costs of opioid use.
摘要
目的
探讨工作场所损伤对阿片类药物依赖、滥用和过量用药（阿片类相关发病率）的影响，以及损伤严重程度是否会增加这些健康影响的风险。
方法
我们使用 MarketScan 数据库对受伤和倾向评分匹配的未受伤工人进行随访，这些工人均无先前的阿片类相关诊断。我们使用 Cox 比例风险模型，研究工作场所损伤对阿片类相关发病率的影响。
结果
受伤工人发生阿片类相关发病率的风险是匹配未受伤工人的 1.79 倍（95%CI 1.89 至 3.60）。对于仅医疗性损伤和导致失时的损伤工人，其风险分别为未受伤工人的 1.54 倍（95%CI 1.02 至 2.32）和 2.91 倍（95%CI 1.75 至 4.84）。
结论
减少工作场所损伤或损伤严重程度，以及努力确保为受伤工人开具适当的阿片类药物处方，可能有助于降低阿片类药物使用带来的社会成本。
相似文献
1
Impact of workplace injury on opioid dependence, abuse, illicit use and overdose: a 36-month retrospective study of insurance claims.工作场所伤害对阿片类药物依赖、滥用、非法使用和过量用药的影响：36 个月保险索赔回顾性研究。
Occup Environ Med. 2020 Sep;77(9):648-653. doi: 10.1136/oemed-2020-106535. Epub 2020 Apr 24.
2
Factors Associated With Persistent Opioid Use Among Injured Workers' Compensation Claimants.与受伤工人赔偿索赔者中持续性阿片类药物使用相关的因素。
JAMA Netw Open. 2018 Oct 5;1(6):e184050. doi: 10.1001/jamanetworkopen.2018.4050.
3
Prescription opioid overdose and adverse effect hospitalisations among injured workers in eight states (2010-2014).在八个州（2010-2014 年），因处方类阿片类药物过量和不良反应而住院的受伤工人。
Occup Environ Med. 2020 Jul;77(7):439-445. doi: 10.1136/oemed-2020-106472. Epub 2020 Apr 10.
4
Prescription opioid use by injured workers in Tennessee: a descriptive study using linked statewide databases.田纳西州受伤工人的处方阿片类药物使用情况：使用全州范围的数据库进行描述性研究。
Ann Epidemiol. 2019 Apr;32:7-13. doi: 10.1016/j.annepidem.2019.02.001. Epub 2019 Feb 14.
5
Do Injured Workers Receive Opioid Prescriptions Outside the Workers' Compensation System?: The Case of Private Group Health Insurances.受伤工人是否会在工人赔偿制度之外获得阿片类药物处方？以私人团体健康保险为例。
J Occup Environ Med. 2020 Sep;62(9):e515-e522. doi: 10.1097/JOM.0000000000001961.
6
Early High-Risk Opioid Prescribing and Persistent Opioid Use in Australian Workers with Workers' Compensation Claims for Back and Neck Musculoskeletal Disorders or Injuries: A Retrospective Cohort Study.澳大利亚因背部和颈部肌肉骨骼疾病或损伤提出工伤赔偿申请的工人中早期高风险阿片类药物处方与持续阿片类药物使用情况：一项回顾性队列研究
CNS Drugs. 2025 May;39(5):499-512. doi: 10.1007/s40263-025-01169-5. Epub 2025 Mar 6.
7
Suicide and drug-related mortality following occupational injury.职业伤害后的自杀和与药物相关的死亡率。
Am J Ind Med. 2019 Sep;62(9):733-741. doi: 10.1002/ajim.23021. Epub 2019 Jul 12.
8
Prescription opioids for occupational injury: results from workers' compensation claims records.用于职业伤害的处方阿片类药物：来自工伤赔偿申请记录的结果
Pain Med. 2014 Sep;15(9):1549-57. doi: 10.1111/pme.12421. Epub 2014 Mar 18.
9
Incidence and costs of family member hospitalization following injuries of workers' compensation claimants.工人赔偿索赔人受伤后家庭成员住院的发生率和费用。
Am J Ind Med. 2012 Nov;55(11):1028-36. doi: 10.1002/ajim.22110. Epub 2012 Sep 11.
10
Occupational patterns of opioid-related harms comparing a cohort of formerly injured workers to the general population in Ontario, Canada.在加拿大安大略省，将一组曾经受伤的工人与普通人群进行比较，分析阿片类药物相关危害的职业模式。
Can J Public Health. 2024 Dec;115(6):851-861. doi: 10.17269/s41997-024-00882-w. Epub 2024 Apr 24.
引用本文的文献
1
The Association Between Employment in Coal Mining and History of Injury, Current Pain, and Prescription Opioid Use.煤矿就业与受伤史、当前疼痛及处方阿片类药物使用之间的关联。
Am J Ind Med. 2025 Jan;68(1):76-88. doi: 10.1002/ajim.23679. Epub 2024 Nov 28.
2
Risk of opioid-related harms by occupation within a large cohort of formerly injured workers in Ontario, Canada: findings from the Occupational Disease Surveillance System.加拿大安大略省一个大型曾受伤工人队列中职业相关的阿片类药物相关伤害风险：职业疾病监测系统的研究结果。
Occup Environ Med. 2024 Oct 23;81(10):507-514. doi: 10.1136/oemed-2024-109458.
3
Opioid-related mortality after occupational injury in Washington State: accounting for preinjury opioid use.华盛顿州职业伤害后与阿片类药物相关的死亡率：考虑到受伤前阿片类药物的使用情况。
Occup Environ Med. 2024 Oct 23;81(10):515-521. doi: 10.1136/oemed-2024-109606.
4
Occupational patterns of opioid-related harms comparing a cohort of formerly injured workers to the general population in Ontario, Canada.在加拿大安大略省，将一组曾经受伤的工人与普通人群进行比较，分析阿片类药物相关危害的职业模式。
Can J Public Health. 2024 Dec;115(6):851-861. doi: 10.17269/s41997-024-00882-w. Epub 2024 Apr 24.
5
Alignment of substance use community benefit prioritization and service lines in US hospitals: a cross-sectional study.美国医院物质使用社区效益优先事项与服务项目的一致性：一项横断面研究。
Addict Sci Clin Pract. 2024 Feb 13;19(1):11. doi: 10.1186/s13722-024-00442-0.
6
An integrated LSTM-HeteroRGNN model for interpretable opioid overdose risk prediction.基于集成 LSTM-HeteroRGNN 的可解释阿片类药物过量风险预测模型。
Artif Intell Med. 2023 Jan;135:102439. doi: 10.1016/j.artmed.2022.102439. Epub 2022 Nov 3.
7
Increased all-cause mortality following occupational injury: a comparison of two states.职业伤害后全因死亡率增加：两个州的比较。
Occup Environ Med. 2022 Dec;79(12):816-823. doi: 10.1136/oemed-2022-108481. Epub 2022 Oct 17.
8
Mortality following workplace injury: Quantitative bias analysis.工作场所伤害后的死亡率：定量偏倚分析。
Ann Epidemiol. 2021 Dec;64:155-160. doi: 10.1016/j.annepidem.2021.09.015. Epub 2021 Oct 1.
9
Do Injured Workers Receive Opioid Prescriptions Outside the Workers' Compensation System?: The Case of Private Group Health Insurances.受伤工人是否会在工人赔偿制度之外获得阿片类药物处方？以私人团体健康保险为例。
J Occup Environ Med. 2020 Sep;62(9):e515-e522. doi: 10.1097/JOM.0000000000001961.
本文引用的文献
1
Increased overall and cause-specific mortality associated with disability among workers' compensation claimants with low back injuries.与腰背部损伤工人赔偿索赔者的残疾相关的总死亡率和特定原因死亡率增加。
Am J Ind Med. 2020 Mar;63(3):209-217. doi: 10.1002/ajim.23083. Epub 2019 Dec 13.
2
Global patterns of opioid use and dependence: harms to populations, interventions, and future action.全球阿片类药物使用和依赖模式：对人群的危害、干预措施和未来行动。
Lancet. 2019 Oct 26;394(10208):1560-1579. doi: 10.1016/S0140-6736(19)32229-9. Epub 2019 Oct 23.
3
Opioid-related overdose deaths by industry and occupation-Massachusetts, 2011-2015.行业和职业相关的阿片类药物过量死亡-马萨诸塞州，2011-2015 年。
Am J Ind Med. 2019 Oct;62(10):815-825. doi: 10.1002/ajim.23029. Epub 2019 Jul 26.
4
Prevalence and Risk Factors Associated With Long-term Opioid Use After Injury Among Previously Opioid-Free Workers.受伤前未使用过阿片类药物的工人受伤后长期使用阿片类药物的流行率和相关风险因素。
JAMA Netw Open. 2019 Jul 3;2(7):e197222. doi: 10.1001/jamanetworkopen.2019.7222.
5
Suicide and drug-related mortality following occupational injury.职业伤害后的自杀和与药物相关的死亡率。
Am J Ind Med. 2019 Sep;62(9):733-741. doi: 10.1002/ajim.23021. Epub 2019 Jul 12.
6
Trends and Patterns of Geographic Variation in Opioid Prescribing Practices by State, United States, 2006-2017.2006-2017 年美国各州阿片类药物处方实践的地域差异趋势和模式。
JAMA Netw Open. 2019 Mar 1;2(3):e190665. doi: 10.1001/jamanetworkopen.2019.0665.
7
Factors Associated With Persistent Opioid Use Among Injured Workers' Compensation Claimants.与受伤工人赔偿索赔者中持续性阿片类药物使用相关的因素。
JAMA Netw Open. 2018 Oct 5;1(6):e184050. doi: 10.1001/jamanetworkopen.2018.4050.
8
Drug and Opioid-Involved Overdose Deaths - United States, 2013-2017.药物和阿片类药物滥用相关的过量死亡-美国，2013-2017 年。
MMWR Morb Mortal Wkly Rep. 2018 Jan 4;67(5152):1419-1427. doi: 10.15585/mmwr.mm675152e1.
9
Opioid and Benzodiazepine Use Before Injury Among Workers in Washington State, 2012 to 2015.2012 年至 2015 年期间华盛顿州工人受伤前阿片类药物和苯二氮䓬类药物的使用情况。
J Occup Environ Med. 2018 Sep;60(9):820-826. doi: 10.1097/JOM.0000000000001346.
10
Overdose Deaths Involving Opioids, Cocaine, and Psychostimulants - United States, 2015-2016.2015 - 2016年美国涉及阿片类药物、可卡因和精神兴奋剂的过量用药死亡情况
MMWR Morb Mortal Wkly Rep. 2018 Mar 30;67(12):349-358. doi: 10.15585/mmwr.mm6712a1.
Zotero 插件